Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Evolutionary dynamics of carbapenem-resistant Acinetobacter baumannii circulating in Chilean hospitals

Full text
Author(s):
Show less -
Opazo-Capurro, Andres [1, 2] ; San Martin, Ivan [1] ; Quezada-Aguiluz, Mario [1] ; Morales-Leon, Felipe [1, 3] ; Dominguez-Yevenes, Mariana [1] ; Lima, Celia A. [1] ; Esposito, Fernanda [4] ; Cerdeira, Louise [4] ; Bello-Toledo, Helia [1] ; Lincopan, Nilton [5, 4] ; Gonzalez-Rocha, Gerardo [1, 2]
Total Authors: 11
Affiliation:
[1] Univ Concepcion, Fac Ciencias Biol, Dept Microbiol, LIAA, UdeC, Concepcion - Chile
[2] Millennium Nucleus Collaborat Res Bacterial Resis, Santiago - Chile
[3] Univ Concepcion, Fac Farm, Dept Farm, Concepcion - Chile
[4] Univ Sao Paulo, Sch Pharm, Dept Clin Anal, Sao Paulo - Brazil
[5] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil
Total Affiliations: 5
Document type: Journal article
Source: INFECTION GENETICS AND EVOLUTION; v. 73, p. 93-97, SEP 2019.
Web of Science Citations: 4
Abstract

We analyze the evolutionary dynamics of ninety carbapenem-resistant Acinetobacter baumannii (CRAB) isolates collected between 1990 and 2015 in Chile. CRAB were identified at first in an isolate collected in 2005, which harbored the ISAba1-bla(OAX-69) arrangement. Later, OXA-58- and OXA-23-producing A. baumannii strains emerged in 2007 and 2009, respectively. This phenomenon was associated with variations in the epidemiology of OXA-type carbapenemases, linked to nosocomial lineages belonging to ST109, ST162, ST15 (CC15) and ST318 (CC15). (AU)

FAPESP's process: 16/08593-9 - Pan-Resistome of beta-lactamase (KPC-2, CTX-M-8, CTX-M-15)-producing Klebsiella pneumoniae and Escherichia coli isolates endemic in Brazil
Grantee:Nilton Erbet Lincopan Huenuman
Support Opportunities: Regular Research Grants