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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Electrochemical sensing based on DNA nanotechnology

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Author(s):
Kogikoski, Jr., Sergio [1] ; Paschoalino, Waldemir J. [1] ; Cantelli, Lory [1] ; Silva, Wilgner [1] ; Kubota, Lauro T. [1]
Total Authors: 5
Affiliation:
[1] State Univ Campinas UNICAMP, Inst Chem, Dept Analyt Chem, POB 6154, BR-13083970 Campinas, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: TRAC-TRENDS IN ANALYTICAL CHEMISTRY; v. 118, p. 597-605, SEP 2019.
Web of Science Citations: 0
Abstract

Electrochemical sensing is one of the major areas in analytical chemistry, since it is easy, reliable, and cheap compared to other analytical techniques. In this way, using DNA to develop novel electrochemical sensing devices bring many advantages compared to other biomolecules. However, the electrochemical properties of DNA are still under discovery. Herein we show three different properties of DNA, which were already studied by electrochemistry, and that can be further explored: (1) the DNA conductivity, derived from the base pair stacking enabling DNA to be a molecular wire; (2) DNA computing, derived from the interaction between different DNA sequences enabling the performance of logic to perform analytical operations; and (3) DNA self-assembly, due to base pairing, DNA can form nanostructures that can provide better electrochemical control. Finally, some perspectives for the topic will be discussed, focusing mainly in the interdisciplinary use of DNA nanostructures in electrochemistry. (C) 2019 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
Grantee:Marco Aurelio Zezzi Arruda
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 16/14507-8 - Structural and Electrochemical Studies of Nanostructures films based on DNA
Grantee:Sergio Kogikoski Junior
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 17/05213-3 - Investigation of the electrocatalytic activity of sensors based on graphene oxide decorated with Pt, Au or Ag nanoparticles by scanning electrochemical microscopy.
Grantee:Waldemir José Paschoalino Junior
Support Opportunities: Scholarships in Brazil - Post-Doctoral
FAPESP's process: 13/22127-2 - Development of novel materials strategic for integrated analytical devices
Grantee:Lauro Tatsuo Kubota
Support Opportunities: Research Projects - Thematic Grants