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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

X-Ray Characterization of Pharmaceutical and Cosmetic Lipidic Nanoparticles for Cutaneous Application

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Carducci, Federica [1] ; Casadei, Bruna Renata [2] ; Mariani, Paolo [1] ; Barbosa, Leandro Ramos Souza [2]
Total Authors: 4
[1] Univ Politecn Marche, Dipartimento Sci Vita & Ambiente, Ancona - Italy
[2] Univ Sao Paulo, Dept Fis Geral, Inst Fis, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Review article
Source: CURRENT PHARMACEUTICAL DESIGN; v. 25, n. 21, p. 2364-2374, 2019.
Web of Science Citations: 2

Starting from the second half of the 1900s, the advent of nanotechnology in medicine has provoked a profound revolution in this area; at present, nanomedicine delivered a remarkably large set of research and clinically useful tools as diagnostic devices, contrast agents, analytical tools, physical therapy applications, and drug-delivery vehicles. Concerning nanoformulations for drug delivery, they are constituted by nanoparticles with dimensions lower than 1 mu m, usually characterized by improved pharmacokinetics, taking advantage of specific targeting. and reduced side effects. The contributors to the present chapter arc reviewing a range of papers related to the structural characterization of nanoformulations by X-ray diffraction techniques. The whole of the considered papers underlines the essential role that biophysical techniques have acquired as an essential prerequisite to understanding stability, bioavailability, and lipid, biopolymer, and drug organization in nanoformulations. (AU)

FAPESP's process: 15/15822-1 - Physicochemical and structural properties of Ionic Liquids and drugs interacting with biologicaly relevant systems.
Grantee:Leandro Ramos Souza Barbosa
Support type: Regular Research Grants