Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Mycobacterium tuberculosis spoligotypes and drug-resistant characterization from Beira compared to genotypes circulating in Mozambique

Full text
Author(s):
Lívia Maria Pala Anselmo [1] ; Emilyn Costa Conceição [2] ; Evangelina Namburete ; Cinara Feliciano [4] ; Silvana Spindola [5] ; Christophe Sola [6] ; Valdes Roberto Bollela [7]
Total Authors: 7
Affiliation:
[1] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Medicina Interna - Brasil
[2] Universidade Federal do Rio de Janeiro. Instituto de Microbiologia Paulo Góes - Brasil
[4] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Medicina Interna - Brasil
[5] Universidade Federal de Minas Gerais. Faculdade de Medicina. Departamento de Medicina Interna - Brasil
[6] Université Paris-Saclay. Institute for Integrative Biology of the Cell (I2BC). CEA, CNRS, Univ. Paris-Sud - França
[7] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Medicina Interna - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Revista da Sociedade Brasileira de Medicina Tropical; v. 52, 2019-11-25.
Abstract

Abstract INTRODUCTION Mozambique is one of three countries with high prevalence of tuberculosis (TB), TB/human immunodeficiency virus coinfection, and multidrug-resistant TB. We aimed to describe Mycobacterium tuberculosis spoligotypes circulating among drug resistant (DR) strains from Beira, Mozambique comparing them with genotypes in the country. METHODS: We performed spoligotyping of 79 M. tuberculosis suspected of DR-TB compared all spoligotype patterns published on the international database and PubMed. RESULTS: Both in Beira and Mozambique (n=578), the main clades were Latin-American-Mediterranean, East-African-Indian, Beijing and T, with no extensively DR TB cases. CONCLUSIONS: Beira and Mozambique share the same population genetic structure of M. tuberculosis. (AU)

FAPESP's process: 15/13333-3 - Molecular epidemiology of multidrug resistant tuberculosis through whole genome sequencing
Grantee:Valdes Roberto Bollela
Support Opportunities: Regular Research Grants