Severity of oral lichen planus and oral lichenoid lesions is associated with anxiety

Author(s):Show less -

Zucoloto, Miriane Lucindo ^[1] ; Warikoda Shibakura, Matheus Eiji ^[2] ; Pavanin, Jefferson Veronezi ^[2] ; Garcia, Fernanda Teixeira ^[2] ; da Silva Santos, Paulo Sergio ^[3] ; Maciel, Aloizio Premoli ^[3] ; Gallo, Camila de Barros ^[4] ; Souza, Nathalia Vilela ^[4] ; Alencar Ramos Innocentini, Lara Maria ^{[2, 5]} ; Martins Humberto, Janaina Silva ^[2] ; Fragoso Motta, Ana Carolina ^[2]

Affiliation

^[1] Univ Sao Paulo, Ribeirao Preto Sch Med, Dept Social Med, Ribeirao Preto, SP - Brazil

^[2] Univ Sao Paulo, Sch Dent Ribeirao Preto, Dept Stomatol Publ Oral Hlth & Forens Dent, Div Oral Diag, Av Caf S-N, BR-14040904 Ribeirao Preto, SP - Brazil

^[3] Univ Sao Paulo, Bauru Sch Dent, Dept Surg Stomatol Pathol & Radiol, Bauru, SP - Brazil

^[4] Univ Sao Paulo, Sch Dent, Dept Stomatol, Sao Paulo, SP - Brazil

^[5] Univ Sao Paulo, Ribeirao Preto Clin Hosp, Ribeirao Preto Sch Med, Div Dent & Stomatol, Ribeirao Preto, SP - Brazil

• Document type: Journal article
• Source: CLINICAL ORAL INVESTIGATIONS; v. 23, n. 12, p. 4441-4448, DEC 2019.
• Web of Science Citations: 0

Abstract

Objectives Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are chronic inflammatory diseases whose symptoms can impair patient's quality of life (QoL). Psychological factors seem to play an important role in these diseases. This study aimed to determine the impact of oral health and anxiety levels on the QoL of patients with OLP and OLL. Patients and methods This was a cross-sectional study composed of OLP and OLL patients and a control group matched by age and sex with no autoimmune/inflammatory or malignant oral lesions. Anxiety levels and oral health impact on QoL were assessed using the Hamilton Anxiety Scale (HAM-A) and the Oral Health Impact Profile-14 (OHIP-14), respectively. The instruments were filled through personal interview before starting the treatment for oral lesions. Results A total of 87 patients diagnosed with OLP (n = 45) and OLL (n = 42), and 87 controls were included in the study. Statistical differences were observed for the psychic and somatic anxiety dimensions between severities of diseases. Patients with OLP or OLL had higher scores for the OHIP-14 dimensions physiological discomfort and social limitation compared with controls. In addition, higher scores for physical pain, physical disability, social disability, and handicap were detected among patients with greater severity. Conclusion Greater severity of OLP and OLL seems to be associated with increased levels of anxiety, higher scores of oral health impact profile, and decreased QoL. (AU)

• FAPESP's process: 14/11883-3 - Clinical, histopathological and immunopathological profile of patients presenting oral lichen planus
• Grantee: Ana Carolina Fragoso Motta
• Support Opportunities: Regular Research Grants
• FAPESP's process: 14/14576-4 - Use of direct immunofluorescence as a diagnostic adjunct test in patients presentin oral lichen planus
• Grantee: Yasmin Yamanaka
• Support Opportunities: Scholarships in Brazil - Scientific Initiation