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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Identification and genomic features of halotolerant extended-spectrum-beta-lactamase (CTX-M)-producing Escherichia coli in urban-impacted coastal waters, Southeast Brazil

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Author(s):
Fernandes, Miriam R. [1] ; Sellera, Fabio P. [2] ; Moura, Quezia [3] ; Esposito, Fernanda [1] ; Sabino, Caetano P. [1] ; Lincopan, Nilton [4, 1]
Total Authors: 6
Affiliation:
[1] Univ Sao Paulo, Fac Pharmaceut Sci, Dept Clin Anal, Sao Paulo - Brazil
[2] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Internal Med, Sao Paulo - Brazil
[3] Fed Univ Grande Dourados, Fac Hlth Sci, Dourados, MS - Brazil
[4] Univ Sao Paulo, Inst Biomed Sci, Dept Microbiol, Sao Paulo - Brazil
Total Affiliations: 4
Document type: Journal article
Source: Marine Pollution Bulletin; v. 150, JAN 2020.
Web of Science Citations: 0
Abstract

We report the occurrence and genomic analysis of extended-spectrum beta-lactamase (CTX-M)-producing Escherichia coli in anthropogenically polluted coastal waters of Southeast Brazil. E. coli strains belonging to sequence types (STs) ST10, ST38, ST155 and ST1284 exhibited a wide resistome, with genes conferring resistance to medically relevant antimicrobials and heavy metals, and a halophilic behavior (tolerance to 9-10% NaCl). These findings suggest a heavy contamination in this area by critical priority bacteria adapted to marine environments, which might have negative impacts on human and ocean health. (AU)

FAPESP's process: 15/13527-2 - Ancestral relationship, pan-resistoma plasmid of Escherichia coli producing b-lactamases of extended spectrum (CTX-M) and of plasmid curing methods
Grantee:Miriam Rodriguez Fernandes
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 16/08593-9 - Pan-Resistome of beta-lactamase (KPC-2, CTX-M-8, CTX-M-15)-producing Klebsiella pneumoniae and Escherichia coli isolates endemic in Brazil
Grantee:Nilton Erbet Lincopan Huenuman
Support type: Regular Research Grants
FAPESP's process: 16/03044-7 - Genetic diversity, virulence genes and antimicrobial resistance of Salmonella spp. isolated from poultry slaughterhouse
Grantee:Daniel Farias Marinho Do Monte
Support type: Scholarships in Brazil - Doctorate