Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The role of water on the electronic transport in graphene nanogap devices designed for DNA sequencing

Full text
Author(s):
Martins, Ernane de Freitas [1, 2] ; Amorim, Rodrigo G. [3] ; Feliciano, Gustavo Troiano [4] ; Scheicher, Ralph Hendrik [5] ; Rocha, Alexandre Reily [2]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Inst Phys, Sao Paulo, SP - Brazil
[2] Sao Paulo State Univ UNESP, Inst Theoret Phys, Campus Sao Paulo, Sao Paulo - Brazil
[3] Univ Fed Fluminense, Dept Fis, ICEx, Volta Redonda, RJ - Brazil
[4] Sao Paulo State Univ UNESP, Inst Chem, Campus Araraquara, Araraquara, SP - Brazil
[5] Uppsala Univ, Dept Phys & Astron, Div Mat Theory, SE-75120 Uppsala - Sweden
Total Affiliations: 5
Document type: Journal article
Source: Carbon; v. 158, p. 314-319, MAR 2020.
Web of Science Citations: 0
Abstract

Innovative methodologies for reliably and inexpensively sequencing DNA can lead to a new era of personalized medicine. In this work, we performed a theoretical investigation of a nanogap-based all electronic DNA sequencing device. To do so, we used a nitrogen-terminated nanogap on a graphene sheet with the aqueous environment fully taken into account. Our investigation is performed using a hybrid methodology combining quantum and classical mechanics coupled to non-equilibrium Green's functions for solving the electron transport across the device. The obtained results show that the DNA nucleotides can be both detected and distinguished in such a device, which indicates that it can be used as a DNA sequencing device providing very high sensitivity and selectivity. Furthermore, our results show that water plays a major role in electronic transport in nanoscopic tunneling devices, not only from an electrostatics point of view, but also by providing states that significantly increase the conductance in nanogap-based DNA sequencing devices. (C) 2019 Elsevier Ltd. All rights reserved. (AU)

FAPESP's process: 17/02317-2 - Interfaces in materials: electronic, magnetic, structural and transport properties
Grantee:Adalberto Fazzio
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 16/01343-7 - ICTP South American Institute for Fundamental Research: a regional center for theoretical physics
Grantee:Nathan Jacob Berkovits
Support Opportunities: Special Projects