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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Photobiomodulation effect on local hemoglobin concentration assessed by near-infrared spectroscopy in humans

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Author(s):
Linares, Stephanie Nogueira [1] ; Beltrame, Thomas [2, 1] ; Ferraresi, Cleber [3] ; Galdino, Gabriela Aguiar Mesquita [1] ; Catai, Aparecida Maria [1]
Total Authors: 5
Affiliation:
[1] Univ Fed Sao Carlos, Cardiovasc Phys Therapy Lab, Dept Phys Therapy, Sao Paulo - Brazil
[2] Univ Estadual Campinas, Inst Comp, Sao Paulo - Brazil
[3] Univ Brasil, Biomed Engn Postgrad Program, Sao Paulo - Brazil
Total Affiliations: 3
Document type: Journal article
Source: Lasers in Medical Science; v. 35, n. 3, p. 641-649, APR 2020.
Web of Science Citations: 1
Abstract

Exposure of biological tissue to photobiomodulation therapy (PBMT) seems to increase the oxygen availability and mitochondrial electrochemical activity. With the advancement of new technologies, such as near-infrared spectroscopy (NIRS), information can be obtained about the balance between oxygen utilization and delivery by assessing local oxy- ({[}O(2)Hb]) and deoxy-myohemoglobin ({[}HHb]) concentrations, both measured in micromolars (mu M). Consequently, NIRS can be used to study ({''}in vivo{''}) PBMT effects on the oxidative system, including oxygen availability. Thus, the main objective of the present study was to use NIRS to investigate the acute effects of PBMT by light-emitting diode (LED) on the oxygen delivery and utilization in humans. Twelve healthy young participants were treated with a LED device (850 nm, 50 mW, 2 J) and placebo applied over the proximal third of the flexor carpi ulnaris muscle of the left or right forearm selected in a random order. The LED was applied in direct contact with skin and the device was switched on for 40 s in 4 different interventions (I-1, I-2, I-3 and I-4) with a 3-min interval between interventions. The placebo condition was considered as the period before the first PBMT. The NIRS device was used to evaluate the relative changes in {[}O(2)Hb] and {[}HHb] before and after placebo and interventions. We found that PBMT statistically increased the {[}O(2)Hb] in 0.39 mu M. These results demonstrate the potential of PBMT to increase oxygen availability. (AU)

FAPESP's process: 17/09639-5 - Exploring machine learning techniques for aerobic system analysis with applicability for cardiorespiratory rehabilitation programs
Grantee:Thomas Beltrame
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/07953-3 - Evaluation of acute effect of phototherapy with Light Emitting Diode (led) on muscle and pulmonary oxygen consumption in patients with diabetes mellitus
Grantee:Aparecida Maria Catai
Support type: Regular Research Grants
FAPESP's process: 18/19016-8 - Associations between aerobic power and fitness
Grantee:Thomas Beltrame
Support type: Scholarships abroad - Research Internship - Post-doctor