Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Clinicopathological analysis of oral Burkitt's lymphoma in pediatric patients: A systematic review

Full text
Author(s):
Rodrigues-Fernandes, Carla Isabelly [1] ; Perez-de-Oliveira, Maria Eduarda [1] ; Aristizabal Arboleda, Lady Paola [1] ; Fonseca, Felipe Paiva [1, 2, 3] ; Lopes, Marcio Ajudarte [1] ; Vargas, Pablo Agustin [1, 3] ; Santos-Silva, Alan Roger [1]
Total Authors: 7
Affiliation:
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Oral Diag, Semiol & Oral Pathol Areas, Ave Limeira 901, BR-13414903 Piracicaba, SP - Brazil
[2] Univ Fed Minas Gerais, Sch Dent, Dept Oral Surg & Pathol, BR-31270901 Belo Horizonte, MG - Brazil
[3] Univ Pretoria, Dept Oral Biol & Oral Pathol, Pretoria - South Africa
Total Affiliations: 3
Document type: Journal article
Source: International Journal of Pediatric Otorhinolaryngology; v. 134, JUL 2020.
Web of Science Citations: 0
Abstract

The aim of this study was to integrate the available data regarding pediatric Burkitt's lymphoma (BL) of the oral cavity. A systematic review was conducted following PRISMA guidelines, through a specific search strategy. Twenty-nine publications were included in this study, resulting in a total of 144 cases. Oral BL was predominantly found in males (75.7%). The mandible was the most involved site (37.5%), and all cases clinically exhibited a swelling. Presence of EBV was observed in 33.3% of the cases, and 4 cases reported HIV-positive patients (33.3%). Chemotherapy was the leading treatment choice for oral BL (94.9%), and the overall 5-year survival was 54.3%. Regarding the quality assessment of the studies, most (19 studies; 65.5%) were classified as an overall moderate risk of bias. In conclusion, the clinicopathological characteristics of oral BL in the pediatric population comprise the sporadic and intermediate subtypes. Despite its aggressiveness, this malignancy presents a moderate overall survival. (AU)

FAPESP's process: 17/14880-3 - Clinicopathological and immunohistochemical analysis of follicular lymphoid hyperplasias and lymphomas of the oral cavity
Grantee:Oslei Paes de Almeida
Support Opportunities: Regular Research Grants