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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Impact of obesity on walking capacity and cardiovascular parameters in patients with peripheral artery disease: A cross-sectional study

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Author(s):
Kanegusuku, Helcio ; Cucato, Gabriel G. ; Domiciano, Romulo M. ; Longano, Paulo ; Puech-Leao, Pedro ; Wolosker, Nelson ; Ritti-Dias, Raphael M. [1] ; Correia, Marilia A.
Total Authors: 8
Affiliation:
[1] Univ Nove Julho, Rua Vergueiro 235, BR-01504000 Sao Paulo, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: JOURNAL OF VASCULAR NURSING; v. 38, n. 2, p. 66-71, JUN 2020.
Web of Science Citations: 0
Abstract

Background: Patients with peripheral artery disease (PAD) present a high prevalence of obesity and metabolic syndrome, as well as diseases related to cardiovascular dysfunction. However, whether obesity influences walking capacity and cardiovascular function in patients with PAD is poorly understood. Objectives: The objective of this study was to analyze the impact of obesity on walking capacity and cardiovascular parameters in patients with PAD. Design: This is a cross-sectional study. Setting: Patients were recruited from public hospitals of Sao Paulo. Methods: One-hundred two patients with PAD and symptoms of intermittent claudication were recruited and divided into 2 groups according to their body mass index: normal weight (<25 kg/m(2)) and overweight/obese (\$25 kg/m(2)). Patients were submitted to objective (6-minute walk test) and subjective measurements of walking capacity (Walking Impairment Questionnaire). In addition, cardiovascular parameters (office blood pressure, resting heart rate, arterial stiffness, vascular function, and heart rate variability) were obtained. Results: The speed domain of the Walking Impairment Questionnaire was lower in the overweight/obese group compared to the normal weight group (32 +/- 20 vs 21 +/- 16, respectively, P < .01). Resting heart rate was higher in overweight/obese patients (61 +/- 10 vs 70 +/- 12, respectively, P < .01). However, no other walking capacity or cardiovascular parameter variables were related to obesity in patients with PAD. Conclusion: Obesity influences resting heart rate and walking speed in patients with PAD. (AU)

FAPESP's process: 16/16425-9 - Effects of handgrip isometric training on blood pressure, endothelial function and cardiac autonomic modulation in patients with peripheral artery disease: a randomized controlled study.
Grantee:Raphael Mendes Ritti Dias
Support Opportunities: Regular Research Grants