| Full text | |
| Author(s): Show less - |
Raymundo-Pereira, Paulo A.
[1]
;
Silva, Tiago A.
[2]
;
Caetano, Fabio R.
[3]
;
Ribovski, Lais
[1]
;
Zapp, Eduardo
[4]
;
Brondani, Daniela
[4]
;
Bergamini, Marcio F.
[3]
;
Marcolino, Jr., Luiz H.
[3]
;
Banks, Craig E.
[5]
;
Oliveira, Jr., Osvaldo N.
[1]
;
Janegitz, Bruno C.
[6]
;
Fatibello-Filho, Orlando
[7]
Total Authors: 12
|
| Affiliation: | [1] Univ Sao Paulo, Sao Carlos Inst Phys, Sao Carlos, SP - Brazil
[2] Ctr Fed Educ Tecnol Minas Gerais CEFET MG, Dept Met & Quim, BR-35180008 Timoteo, MG - Brazil
[3] Univ Fed Parana UFPR, Dept Quim, Lab Sensores Eletroquim LabSensE, BR-81531980 Curitiba, PR - Brazil
[4] Univ Fed Santa Catarina, Dept Exact Sci & Educ, BR-89036256 Florianopolis, SC - Brazil
[5] Manchester Metropolitan Univ, Fac Sci & Engn, Chester St, Manchester M1 5GD, Lancs - England
[6] Univ Fed Sao Carlos, Dept Nat Sci Math & Educ, BR-13600970 Araras, SP - Brazil
[7] Univ Fed Sao Carlos, Dept Chem, BR-13560970 Sao Carlos, SP - Brazil
Total Affiliations: 7
|
| Document type: | Review article |
| Source: | Analytica Chimica Acta; v. 1139, p. 198-221, DEC 1 2020. |
| Web of Science Citations: | 6 |
| Abstract | |
The detection of phenolic compounds is relevant not only for their possible benefits to human health but also for their role as chemical pollutants, including as endocrine disruptors. The required monitoring of such compounds on-site or in field analysis can be performed with electrochemical biosensors made with polyphenol oxidases (PPO). In this review, we describe biosensors containing the oxidases tyrosinase and laccase, in addition to crude extracts and tissues from plants as enzyme sources. From the survey in the literature, we found that significant advances to obtain sensitive, robust biosensors arise from the synergy reached with a diversity of nanomaterials employed in the matrix. These nanomaterials are mostly metallic nanoparticles and carbon nanostructures, which offer a suitable environment to preserve the activity of the enzymes and enhance electron transport. Besides presenting a summary of contributions to electrochemical biosensors containing PPOs in the last five years, we discuss the trends and challenges to take these biosensors to the market, especially for biomedical applications. (C) 2020 Elsevier B.V. All rights reserved. (AU) | |
| FAPESP's process: | 16/01919-6 - Design and fabrication of nanostructured flexible devices for biomarkers detection |
| Grantee: | Paulo Augusto Raymundo Pereira |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/22214-6 - Towards a convergence of technologies: from sensing and biosensing to information visualization and machine learning for data analysis in clinical diagnosis |
| Grantee: | Osvaldo Novais de Oliveira Junior |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 17/21097-3 - Bee-agriculture interactions: perspectives to sustainable use |
| Grantee: | Osmar Malaspina |
| Support Opportunities: | BIOTA-FAPESP Program - Thematic Grants |
| FAPESP's process: | 17/21898-6 - New conductive devices for application in electrochemical sensing and biosensing |
| Grantee: | Bruno Campos Janegitz |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 20/01050-5 - Development and application of electrochemical and photoelectrochemical sensors for the determination of emerging contaminants in environmental samples |
| Grantee: | Orlando Fatibello Filho |
| Support Opportunities: | Regular Research Grants |