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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Escherichia coli as a Multifaceted Pathogenic and Versatile Bacterium

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Author(s):
Braz, Vania Santos [1] ; Melchior, Karine [1] ; Moreira, Cristiano Gallina [1]
Total Authors: 3
Affiliation:
[1] Sao Paulo State Univ UNESP, Sch Pharmaceut Sci, Dept Biol Sci, Araraquara, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY; v. 10, DEC 21 2020.
Web of Science Citations: 0
Abstract

Genetic plasticity promotes evolution and a vast diversity in Escherichia coli varying from avirulent to highly pathogenic strains, including the emergence of virulent hybrid microorganism. This ability also contributes to the emergence of antimicrobial resistance. These hybrid pathogenic E. coli (HyPEC) are emergent threats, such as O104:H4 from the European outbreak in 2011, aggregative adherent bacteria with the potent Shiga-toxin. Here, we briefly revisited the details of these E. coli classic and hybrid pathogens, the increase in antimicrobial resistance in the context of a genetically empowered multifaceted and versatile bug and the growing need to advance alternative therapies to fight these infections. (AU)

FAPESP's process: 14/06779-2 - Role of chemical signaling and auxiliary mechanisms in Salmonella enterica serovar Typhimurium virulence and other enteropathogens
Grantee:Cristiano Gallina Moreira
Support Opportunities: Research Grants - Young Investigators Grants
FAPESP's process: 19/03049-7 - Transcriptome of the bacterial chemical signaling in Salmonella Typhimurium, emergent global bacterial enteropathogens investigation in São Paulo, and alternative infection model employed to study pathogenesis
Grantee:Cristiano Gallina Moreira
Support Opportunities: Regular Research Grants
FAPESP's process: 18/22412-2 - Technological strategies for administration of an antivirulence compound against salmonellosis in farm animals
Grantee:Vânia Santos Braz
Support Opportunities: Research Grants - Innovative Research in Small Business - PIPE
FAPESP's process: 18/22042-0 - Chemical signaling and virulence in Escherichia coli enterohemorrhagic mediated by members of the microbiota
Grantee:Karine Melchior
Support Opportunities: Scholarships in Brazil - Master