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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Current advances in drug delivery of nanoparticles for respiratory disease treatment

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de Menezes, Beatriz Rossi Canuto [1] ; Rodrigues, Karla Faquine [1] ; Schatkoski, Vanessa Modelski [1] ; Pereira, Raissa Monteiro [1] ; Ribas, Renata Guimaraes [1] ; Montanheiro, Thais Larissa do Amaral [1] ; Thim, Gilmar Patrocinio [1]
Total Authors: 7
[1] Technol Inst Aeronaut ITA, Lab Plasma & Proc LPP, Praca Marechal Eduardo Gomes 50, BR-12228900 Sao Jose Dos Campos, SP - Brazil
Total Affiliations: 1
Document type: Review article
Source: JOURNAL OF MATERIALS CHEMISTRY B; v. 9, n. 7, p. 1745-1761, FEB 21 2021.
Web of Science Citations: 0

Cases of respiratory diseases have been increasing around the world, affecting the health and quality of life of millions of people every year. Chronic respiratory diseases (CRDs) and acute respiratory infections (ARIs) are responsible for many hospital admissions and deaths, requiring sophisticated treatments that facilitate the delivery of therapeutics to specific target sites with controlled release. In this context, different nanoparticles (NPs) have been explored to match this demand, such as lipid, liposome, protein, carbon-based, polymeric, metallic, oxide, and magnetic NPs. The use of NPs as drug delivery systems can improve the efficacy of commercial drugs due to their advantages related to sustained drug release, targeting effects, and patient compliance. The current review presents an updated summary of recent advances regarding the use of NPs as drug delivery systems to treat diseases related to the respiratory tract, such as CRDs and ARIs. The latest applications presented in the literature were considered, and the opportunities and challenges of NPs in the drug delivery field are discussed. (AU)

FAPESP's process: 17/24873-4 - PHBV and hydroxybutyrate functionalized CNT nanocomposite: kinetic study of crystallization and correlation with mechanical properties
Grantee:Thaís Larissa do Amaral Montanheiro
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 18/12035-7 - Mechanical and antimicrobial properties of Ag/PMMA nanocomposite
Grantee:Gilmar Patrocínio Thim
Support type: Regular Research Grants
FAPESP's process: 17/02846-5 - AgVO3/PMMA Nanocomposites: Effect of functionalization with acrilamide on mechanical and antimicrobial properties
Grantee:Beatriz Rossi Canuto de Menezes Rodrigues
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 17/27079-7 - Reinforcement of a wollastonite cement (CaSiO3) by carbon nanotubes for biomedical or dental applications
Grantee:Renata Guimarães Ribas
Support type: Scholarships in Brazil - Doctorate