Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests

Author(s)

Yamane de Oliveira, Cristiane Helga ^[1] ; Jose, Anderson ^[2] ; de Camargo, Anderson Alves ^[1] ; Zanetti Feltrim, Maria Ignez ^[3] ; Athanazio, Rodrigo Abensur ^[4] ; Rached, Samia Zahi ^[4] ; Stelmalch, Rafael ^[4] ; Dal Corso, Simone ^[1]

Affiliation

^[1] Univ Nove de Julho, Programa Posgrad Ciencias Reabilitacao, Sao Paulo, SP - Brazil

^[2] Univ Fed Juiz de Fora, Programa Posgrad Ciencias Reabilitacao & Desempen, Ave Eugenio Nascimento S-N, BR-36038330 Juiz De Fora, MG - Brazil

^[3] Univ Sao Paulo, Serv Fisioterapia, Inst Coracao InCor, Hosp Clin, Fac Med, Sao Paulo, SP - Brazil

^[4] Univ Sao Paulo, Div Pneumol, Inst Coracao InCor, Hosp Clin, Fac Med, Sao Paulo, SP - Brazil

• Document type: Journal article
• Source: Jornal Brasileiro de Pneumologia; v. 47, n. 2 2021.
• Web of Science Citations: 0

Abstract

ABSTRACT Objective: To investigate the validity of field walking tests to identify exercise-induced hypoxemia and to compare cardiorespiratory responses and perceived effort between laboratory-based and field-based exercise tests in subjects with bronchiectasis. Methods: This was a cross-sectional study involving 72 non-oxygen-dependent participants (28 men; mean age = 48.3 ± 14.5 years; and mean FEV1 = 54.1 ± 23.4% of the predicted value). The participants underwent cardiopulmonary exercise testing (CPET) on a treadmill and constant work-rate exercise testing (CWRET) on the same day (1 h apart). In another visit, they underwent incremental shuttle walk testing (ISWT) and endurance shuttle walk testing (ESWT; 1 h apart). Desaturation was defined as a reduction in SpO2 ≥ 4% from rest to peak exercise. Results: CPET results were compared with ISWT results, as were CWRET results with ESWT results. There was no difference in the magnitude of desaturation between CPET and ISWT (−7.7 ± 6.3% vs. −6.6 ± 5.6%; p = 0.10) and between CWRET and ESWT (−6.8 ± 5.8% vs. −7.2 ± 6.3%; p = 0.50). The incremental tests showed an agreement in the magnitude of desaturation in the desaturation and no desaturation groups (42 and 14 participants, respectively; p < 0.01), as did the endurance tests (39 and 16 participants; p < 0.01). The magnitude of desaturation was similar among the participants who did or did not reach at least 85% of the maximum predicted HR. Conclusions: Field exercise tests showed good precision to detect desaturation. Field tests might be an alternative to laboratory tests when the clinical question is to investigate exercise-induced desaturation in subjects with bronchiectasis. (AU)

• FAPESP's process: 14/01902-0 - Effects of pulmonary rehabilitation associated with respiratory physiotherapy vs. respiratory physiotherapy on exercise capacity, peripheral muscle strength, and quality of life in patients with bronchiectasis: randomized controlled trial
• Grantee: Anderson Alves de Camargo
• Support Opportunities: Scholarships in Brazil - Doctorate