| Full text | |
| Author(s): |
Kitagawa, Igor L.
[1, 2]
;
Miyazaki, Celina M.
[3]
;
Pitol-Palin, Leticia
[4]
;
Okamoto, Roberta
[4]
;
de Vasconcellos, Luana M. R.
[5]
;
Constantino, Carlos J. L.
[6]
;
Lisboa-Filho, Paulo N.
[1]
Total Authors: 7
|
| Affiliation: | [1] Sao Paulo State Univ, Sch Sci, Dept Phys, UNESP, BR-17033360 Bauru, SP - Brazil
[2] IFSP Fed Inst Educ, Sci & Technol Sao Paulo, BR-16201407 Birigui, SP - Brazil
[3] Univ Fed Sao Carlos, CCTS, BR-18052780 Sorocaba, SP - Brazil
[4] Sao Paulo State Univ, UNESP, Aracatuba Dent Sch, Dept Basic Sci, BR-16018805 Aracatuba - Brazil
[5] Sao Paulo State Univ, Dept Biosci & Oral Diag, Inst Sci & Technol, UNESP, BR-12245000 Sao Jose Dos Campos, SP - Brazil
[6] Sao Paulo State Univ, Sch Technol & Appl Sci, Dept Phys, UNESP, BR-19060900 Presidente Prudente, SP - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | ACS APPLIED BIO MATERIALS; v. 4, n. 4, p. 3055-3066, APR 19 2021. |
| Web of Science Citations: | 1 |
| Abstract | |
Implant placement is an important repair method in dentistry and orthopedics. Increasing efforts have focused on optimizing the biocompatibility and osseointegration properties of titanium (Ti) and Ti-based alloys. In this work, Ti-based alloys were modified by the layer-by-layer (LbL) technique, which is a simple and versatile method for surface modification. The morphology and chemical structure of LbL films of poly(sodium 4-styrenesulfonate) (PSS) and Ti dioxide (TiO2) nanoparticles were first characterized employing ultraviolet-visible and Fouriertransform infrared spectroscopies as well as atomic force microscopy for further application in Ti-based alloy implants. The changes provoked by the LbL PSS/TiO2 film on the Ti-based alloy surfaces were then investigated by scanning electron microscopy and micro-Raman techniques. Finally, in vivo tests (immunolabeling and biomechanical analysis) performed with screw implants in rats suggested that PSS/TiO2 multilayers promote changes in both topography and chemical surface properties of the screw, providing beneficial effects for osteoblast activity. This simple and relatively low-cost growth process can open up possibilities to improve dental implants and, probably, bone implants in general. (AU) | |
| FAPESP's process: | 14/15093-7 - Study of nanostructured systems by surface plasmon resonance (SPR): applications in biosensing |
| Grantee: | Celina Massumi Miyazaki |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/15035-5 - Adsorption of bisphosphonates and proteins on TiO2 surfaces for bone implants |
| Grantee: | Paulo Noronha Lisboa Filho |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 18/03114-0 - ASSOCIATION OF SYSTEMIC AND LOCAL MEDICAMENT TREATMENT DURING THE PERIMPLANTAR REPAIR PROCESS IN OVARIECTOMIZED RATS CARRIERS OF METABOLIC SYNDROME |
| Grantee: | Roberta Okamoto |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/07296-2 - CDMF - Center for the Development of Functional Materials |
| Grantee: | Elson Longo da Silva |
| Support Opportunities: | Research Grants - Research, Innovation and Dissemination Centers - RIDC |