| Full text | |
| Author(s): |
Chehuen, Marcel da Rocha
[1]
;
Cucato, Gabriel Grizzo
[2]
;
Fernandes de Carvalho, Celso Ricardo
[3]
;
Zerati, Antonio Eduardo
[3]
;
Leicht, Anthony
[4]
;
Wolosker, Nelson
[5]
;
Ritti-Dias, Raphael Mendes
[6]
;
de Moraes Forjaz, Claudia Lucia
[1]
Total Authors: 8
|
| Affiliation: | [1] Univ Sao Paulo, Escola Educ Fis & Esporte, Av Prof Mello Moraes 65, Cidade Univ, BR-05508030 Sao Paulo, SP - Brazil
[2] Northumbria Univ, Newcastle Upon Tyne, Tyne & Wear - England
[3] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Sao Paulo, SP - Brazil
[4] James Cook Univ, Douglas, Qld - Australia
[5] Hosp Israelita Albert Einstein, Sao Paulo, SP - Brazil
[6] Univ Nove Julho, Programa Posgrad Ciencias Reabil, Sao Paulo, SP - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Arquivos Brasileiros de Cardiologia; v. 116, n. 5, p. 898-905, MAY 2021. |
| Web of Science Citations: | 1 |
| Abstract | |
Background: Walking training (WT) improves walking capacity and reduces clinic blood pressure (BP) in patients with peripheral artery disease (PAD), but its effects on ambulatory BP remains unknown. Objective: To investigate the effect of 12 weeks of WT on ambulatory BP and its variability in patients with PAD. Methods: Thirty-five male patients with PAD and claudication symptoms were randomly allocated into two groups: control (n = 16, 30 min of stretching) and WT (n = 19, 15 bouts of 2 min of walking at the heart rate of leg pain threshold interspersed by 2 min of upright rest). Before and after 12 weeks, 24-hour ambulatory BP was assessed. Ambulatory BP variability indices assessed at both time points included the 24-hour standard deviation (SD24), the awake and asleep weighted standard deviation (SDdn), and the 24-hour average real variability (ARV24). Data were analyzed by mixed two-way ANOVAs, considering P<0.05 as significant. Results: After 12 weeks, neither group had significant changes in 24-hour, awake and sleep BPs. The WT decreased systolic and mean BP variabilities (Systolic BP – 13.3±2.8 vs 11.8±2.3, 12.1±2.84 vs 10.7±2.5 and 9.4±2.3 vs 8.8±2.2 mmHg); Mean BP – 11.0±1.7 vs 10.4±1.9, 10.1±1.6 vs 9.1±1.7 and 8.0.±1.7 vs 7.2±1.5 mmHg) for SD24, SDdn and ARV24, respectively). Neither group had significant changes in diastolic BP variabilities after 12 weeks. Conclusions: The WT does not change ambulatory BP levels but decreases ambulatory BP variability in patients with PAD. This improvement may have a favorable impact on the cardiovascular risk of patients with symptomatic PAD. (Arq Bras Cardiol. 2021; 116(5):898-905) (AU) | |
| FAPESP's process: | 15/13800-0 - Walking training in intermittent claudication: responses at rest and after maximal exercise |
| Grantee: | Cláudia Lúcia de Moraes Forjaz |
| Support Opportunities: | Regular Research Grants |