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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Pyrrolizidine alkaloids and other constituents from Emilia fosbergii Nicolson

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Author(s):
Freitas, Jolindo A. [1] ; Ccana-Ccapatinta, V, Gari ; Da Costa, Fernando B. [2]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Lab Pharmacognosy, AsterBioChem Res Team, Av Cafe S-N, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Ccana-Ccapatinta, Gari, V, Univ Sao Paulo, Sch Pharmaceut Sci Ribeirao Preto, Lab Pharmacognosy, AsterBioChem Res Team, Av Cafe S-N, BR-14040903 Ribeirao Preto, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: Biochemical Systematics and Ecology; v. 92, OCT 2020.
Web of Science Citations: 0
Abstract

Emilia fosbergii is a member of the tribe Senecioneae (Asteraceae), most species of which contain pyrrolizidine alkaloids. Notwithstanding, the phytochemistry of E. fosbergii is poorly understood, and pyrrolizidine alkaloids produced by this species have yet to be characterized. In this work, the presence of 11 pyrrolizidine alkaloids, three caffeoylquinic acid derivatives, and six flavonoids were detected by liquid chromatography coupled to high-resolution mass spectrometry analyses. Pyrrolizidine alkaloids of otonecine, retronecine, and platynecine bases are annotated in different parts of the plant. Furthermore, emiline was isolated, possibly indicating that E. fosbergii has a close phylogenetic relationship with E. coccinea. The chemophenetic implications of the presence of pyrrolizidine alkaloids in E. fosbergii and tribe Senecioneae are discussed. (AU)

FAPESP's process: 14/26866-7 - Metabolomics, enzymatic targets and in silico tools in the search of bioactive compounds from plants
Grantee:Fernando Batista da Costa
Support Opportunities: Regular Research Grants