| Full text | |
| Author(s): |
Menezes Barbosa, Paula de Paula
[1]
;
Ruviaro, Amanda Roggia
[2]
;
Martins, Isabela Mateus
[2]
;
Macedo, Juliana Alves
[2]
;
LaPointe, Gisele
[3]
;
Macedo, Gabriela Alves
[1, 2]
Total Authors: 6
|
| Affiliation: | [1] Univ Estadual Campinas, Sch Food Engn, Dept Food Sci, BR-13083862 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Sch Food Engn, Dept Food & Nutr, BR-13083862 Campinas, SP - Brazil
[3] Univ Guelph, Canadian Res Inst Food Safety, Dept Food Sci, Guelph, ON N1G 2W1 - Canada
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | FOOD & FUNCTION; v. 11, n. 10, p. 8996-9009, OCT 1 2020. |
| Web of Science Citations: | 1 |
| Abstract | |
Citrus by-products are inexpensive sources of polyphenols, important bioactive compounds with wide pharmaceutical and food applications. This study aimed to investigate the effect of enzymatic treatment of citrus by-products on the polyphenolic profile of extracts and assess the influence of extracts on the growth and adhesion of probiotics and foodborne pathogenic bacteria and on the inflammatory response of epithelial cells. Enzyme-assisted extraction altered the polyphenolic profile (as assessed by HPLC-DAD), increasing the content of aglycone flavanones (naringenin and hesperetin). Enzymatic extracts and aglycone flavanones exhibited higher antibacterial and prebiotic activities than non-enzymatic extracts and glycoside flavanones. However, a higher content of aglycones was not associated with higher anti-adhesion activity. Citrus extracts significantly (P <= 0.05) decreased the inflammatory response of Caco-2 cells toSalmonellaTyphimurium adhesion. These results support the sustainable reuse of citrus agroindustrial wastes and indicate the potential of citrus extracts in preventing infection by foodborne pathogenic bacteria and inducing proliferation of probiotics in foods and the gut environment. (AU) | |
| FAPESP's process: | 15/04555-2 - Biological process development of rich phenolics extracts from citrus waste industry and evaluation of bioactivity from extracts |
| Grantee: | Gabriela Alves Macedo |
| Support Opportunities: | Regular Research Grants |