Eating habits, sleep, and a proxy for circadian disruption are correlated with dyslipidemia in overweight night workers

Author(s)

Felix Garrido, Ananda Lais ^[1] ; Duarte, Adriana de Sousa ^[1] ; Santana, Patricia Teixeira ^[2] ; Rodrigues, Gabriella Habib ^[3] ; Pellegrino, Pollyanna ^[4] ; Ramos Nogueira, Luciana Fidalgo ^[4] ; Cipolla-Neto, Jose ^[5] ; de Castro Moreno, Claudia Roberta ^{[6, 7]} ; Marqueze, Elaine Cristina ^{[6, 4]}

Affiliation

^[1] Univ Catolica Santos, Ctr Appl Social & Hlth Sci, Nursing, Sao Paulo - Brazil

^[2] Univ Catolica Santos, Ctr Appl Social & Hlth Sci, Pharm, Sao Paulo - Brazil

^[3] Univ Catolica Santos, Ctr Appl Social & Hlth Sci, Nutr, Sao Paulo - Brazil

^[4] Univ Catolica Santos, Dept Epidemiol, Publ Hlth Grad Program, Sao Paulo - Brazil

^[5] Univ Sao Paulo, Inst Biomed Sci, Sao Paulo - Brazil

^[6] Univ Sao Paulo, Sch Publ Hlth, Dept Hlth Life Cycles & Soc, Sao Paulo - Brazil

^[7] Stockholm Univ, Stress Res Inst, Dept Psychol, Stockholm - Sweden

• Document type: Journal article
• Source: NUTRITION; v. 83, MAR 2021.
• Web of Science Citations: 1

Abstract

Objective: The aim of this study was to evaluate the relationship between proxy for circadian disruption, eating habits, sleep characteristics, and dyslipidemic parameters. Methods: This was a randomized, double-blind, crossover controlled clinical trial, and for this study, only baseline data were used. The sample was composed of 36 overweight female nurses who worked on a fixed night shift (12 x 36 h). Linear regression models were used to assess the relationship between the mentioned variables. Results: The participants' average age was 39.4 y (Standard error (SE) 1 y) and the average nighttime sleep duration was 5.76 h (SE 0.16 h). The average chronotype indicated a moderate early type (03:03 h; SE 20 min) and the average social jetlag was 03:42 h (SE 10 min). It was found that 1 h less of nighttime sleep increased very-low-density lipoprotein cholesterol levels by 2.75 mg/dL and triacylglyceride levels by 3.62 mg/dL. Additionally, higher social jetlag was associated with higher low-density lipoprotein cholesterol levels. On the other hand, each additional hour in the chronotype increased high-density lipoprotein cholesterol levels by 3.06 mg/dL and a time interval >2 h between the last meal and sleep onset was associated with higher high-density lipoprotein cholesterol levels. Conclusion: Short duration of nighttime sleep and high social jetlag are risk factors for dyslipidemia, whereas the late type and the longer time interval between the last meal and sleep onset appear to be protective factors for dyslipidemia. (C) 2020 Elsevier Inc. All rights reserved. (AU)

• FAPESP's process: 18/09704-4 - Relationship between social jet lag and diabetes markers in overweight night workers
• Grantee: Adriana de Sousa Duarte
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 14/50457-0 - Melatonin and the control of energy metabolism: basic, clinical and epidemiological research
• Grantee: José Cipolla Neto
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/03624-1 - Association of sleep aspects with macronutrient consumption among night shift nursing professionals with excess weight
• Grantee: Gabriella Habib Rodrigues
• Support Opportunities: Scholarships in Brazil - Scientific Initiation