| Full text | |
| Author(s): |
Santos, Krysthal Marrie dos
[1]
;
Neto, Jorge de Lima
[1]
;
Silva, Luis Paulo Alves da
[1]
;
Reis, Analu Campos
[1]
;
Porto, Ricardo Silva
[1]
;
Lima, Dimas Jose da Paz
[1]
;
Santana, Antonio Euzebio Goulart
[2]
Total Authors: 7
|
| Affiliation: | [1] Univ Fed Alagoas, Chem & Biotechnol Inst, Maceio, Alagoas - Brazil
[2] Univ Fed Alagoas, Ctr Engn & Agr Sci, Rio Largo - Brazil
Total Affiliations: 2
|
| Document type: | Review article |
| Source: | MINI-REVIEWS IN ORGANIC CHEMISTRY; v. 18, n. 6, p. 690-708, 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
This paper presents a short review of synthetic approaches aiming to synthesise (+)Grandisol, the main constituent of grandlure, a pheromone mixture released by the boll weevil, which is proven to exhibit significant biological activity. (+)-Grandisol 1 is among the components of the male-produced pheromone of the boll weevil Anthonomuns grandis, an important pest of cotton crops in Mesoamerica (from the south USA to Argentina). As a result of its biological activity and unique structure, several synthetic approaches have been reported. The aim is to explore remarkable methodologies towards the synthesis of (+)-Grandisol 1. Several methodologies have been applied towards the synthesis of (+)-Grandisol 1, including classical methods for cyclobutane ring construction, which promoted substantial improvements to access this pheromone, as well as a better comprehension of its biological profile. (AU) | |
| FAPESP's process: | 14/50871-0 - INCT 2014: National Institute of Science and Technology of Semiochemicals in Agriculture |
| Grantee: | José Roberto Postali Parra |
| Support Opportunities: | Research Projects - Thematic Grants |