| Full text | |
| Author(s): |
Kisukuri, Camila M.
[1]
;
Fernandes, Vitor A.
[1]
;
Delgado, Jose A. C.
[1]
;
Haering, Andreas P.
[2]
;
Paixao, Marcio W.
[1]
;
Waldvogel, Siegfried R.
[2]
Total Authors: 6
|
| Affiliation: | [1] Fed Univ Sao Carlos UFSCar Sao Carlos, Ctr Excellence Res Sustainable Chem CERSusChem, Dept Chem, BR-13565905 Sao Paulo - Brazil
[2] Johannes Gutenberg Univ Mainz, Dept Chem, Duesbergweg 10-14, D-55128 Mainz - Germany
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | CHEMICAL RECORD; v. 21, n. 9, SI, p. 2502-2525, SEP 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
Electrosynthesis can be considered a powerful and sustainable methodology for the synthesis of small organic molecules. Due to its intrinsic ability to generate highly reactive species under mild conditions by anodic oxidation or cathodic reduction, electrosynthesis is particularly interesting for otherwise challenging transformations. One such challenge is the installation of fluorinated alkyl groups, which has gained significant attention in medicinal chemistry and material science due to their unique physicochemical features. Unsurprisingly, several electrochemical fluoroalkylation methods have been established. In this review, we survey recent developments and established methods in the field of electrochemical mono-, di-, and trifluoromethylation, and perfluoroalkylation of small organic molecules. (AU) | |
| FAPESP's process: | 18/12986-1 - Development of photochemical and electrocatalytic methodologies to the synthesis and modification of heterocyclic scaffolds |
| Grantee: | Camila de Menezes Kisukuri |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 15/17141-1 - Development and Mechanism Studies of New Synthetic Methodologies for the Synthesis of Bioactive Compounds. |
| Grantee: | Ricardo Samuel Schwab |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 14/50249-8 - Green chemistry: sustainable synthetic methods employing benign solvents, safer reagents, and bio-renewable feedstock |
| Grantee: | Arlene Gonçalves Corrêa |
| Support Opportunities: | Research Grants - Research Centers in Engineering Program |
| FAPESP's process: | 19/01973-9 - Exploration of the Asymmetric Induction in Ugi Variations Aiming the Stereoselective Synthesis and Functionalizationof N-Heterocycles |
| Grantee: | Vitor Alcantara Fernandes da Silva |
| Support Opportunities: | Scholarships in Brazil - Doctorate |