Food addiction symptoms and metabolic changes in children and adolescents with the double burden of malnutrition

Author(s)

Squizato de Moraes, Rubia Cartaxo ^[1] ; Sawaya, Ana Lydia ^[2] ; Alves Vieira, Anne Caroline ^[1] ; Grangeiro Pereira, Joicy Karla ^[1] ; de Brito Alves, Jose Luiz ^[1] ; de Luna Freire, Micaelle Oliveira ^[3] ; Filgueiras, Andrea Rocha ^[2] ; Baccin Martins, Vinicius Jose ^[4]

Affiliation

^[1] Univ Fed Paraiba, Dept Nutr, UFPB, Joao Pessoa, Paraiba - Brazil

^[2] Univ Sao Paulo, Dept Physiol, UNIFESP, Sao Paulo - Brazil

^[3] Univ Fed Paraiba, Dept Biotechnol, UFPB, Joao Pessoa, Paraiba - Brazil

^[4] Univ Fed Paraiba, Dept Physiol & Pathol, UFPB, Joao Pessoa, Paraiba - Brazil

• Document type: Journal article
• Source: BRITISH JOURNAL OF NUTRITION; v. 126, n. 12, p. 1911-1918, DEC 28 2021.
• Web of Science Citations: 1

Abstract

The double burden of malnutrition (DBM) has been described in many low-/middle-income countries. We investigated food addiction, thyroid hormones, leptin, the lipid/glucose profile and body composition in DBM children/adolescents. Subjects were allocated into groups according to nutritional status: control (C, n 28), weight excess (WE, n 23) and DBM (WE plus mild stunting, n 22). Both the DBM and WE groups showed higher mean insulin concentrations than the control (DBM = 57 center dot 95 (95 % CI 47 center dot 88, 70 center dot 14) pmol/l, WE = 74 center dot 41 (95 % CI 61 center dot 72, 89 center dot 80) pmol/l, C = 40 center dot 03 (95 % CI 34 center dot 04, 47 center dot 83) pmol/l, P < 0 center dot 001). WE and DBM showed more food addiction symptoms than the control (3 center dot 11 (95 % CI 2 center dot 33, 3 center dot 89), 3 center dot 41 (95 % CI 2 center dot 61, 4 center dot 20) and 1 center dot 66 (95 % CI 0 center dot 95, 2 center dot 37)). In DBM individuals, addiction symptoms were correlated with higher body fat and higher insulin and leptin levels. These data provide preliminary evidence consistent with the suggestion that DBM individuals have a persistent desire to eat, but further studies are required to confirm these results in a larger study. These hormonal changes and high body fat contribute to the development of diabetes in long term. (AU)

• FAPESP's process: 18/04164-1 - Study of the effectiveness of multidisciplinary intervention in overweight adolescents at the Nutrition Education and Recovery Center - Health Multipliers Project - PHASE 2
• Grantee: Ana Lydia Sawaya
• Support Opportunities: Regular Research Grants