| Full text | |
| Author(s): |
Gouveia, M. C. P.
[1]
;
Minto, B. W.
[1]
;
Sargi, L. F.
[1]
;
Souza, R. L.
[2]
;
Pazzini, J. M.
[3]
;
Colodel, E. M.
[2]
;
Silva, V. C. P.
[2]
;
Cassino, P. C.
[1]
;
Dias, L. G. G. G.
[1]
Total Authors: 9
|
| Affiliation: | [1] Univ Estadual Paulista, Fac Ciencias Agr & Vet, Jaboticabal, SP - Brazil
[2] Univ Fed Mato Grosso, Cuiaba, MT - Brazil
[3] Unido Fac Grandes Lagos, Sao Jose Do Rio Preto, SP - Brazil
Total Affiliations: 3
|
| Document type: | Journal article |
| Source: | Arquivo Brasileiro de Medicina Veterinária e Zootecnia; v. 73, n. 6, p. 1315-1323, NOV-DEC 2021. |
| Web of Science Citations: | 0 |
| Abstract | |
ABSTRACT The aim of this study was to evaluate the topical application of alcoholic extracts of Dipteryx alata Vogel almonds and bark in skin wound healing in mice. Fifty-four C57BL/6 mice were equally distributed into three groups: Control, Almond, and Bark. A 9 mm skin fragment was resected from the dorsal region of the animals’ thorax. The wounds were submitted to topical application of base cream (vehicle), 10% hydroalcoholic almond extract, or bark extract twice a day. Macroscopic, histological, and immunohistochemical evaluations were conducted on the 7th, 14th, and 21st postoperative days. No significant difference was observed regarding skin wound area among groups, with the parameter presenting only a temporal effect on healing (p>0.05). The almond and control groups exhibited more intense collagenization than the bark group (p<0.05). Dipteryx alata Vogel showed to be inert in the wound healing process in mice. (AU) | |
| FAPESP's process: | 18/25061-6 - Evaluation of Wound healing in mice treated with alcoholic extract from Dipterix alata Vogel (Leguminosae) |
| Grantee: | Marcelo Candido Portilho Gouveia |
| Support Opportunities: | Scholarships in Brazil - Master |