Effects of Aging on Hemodynamic Kinetics in Different Intensities of Dynamic Exercise

Author(s)

Borghi-Ricardo, Matheus ^[1] ; Simoes, Rodrigo Polaquini ^[2] ; Santos, Daniel Augusto ^[3] ; Archiza, Bruno ^[3] ; Borghi-Silva, Audrey ^[2]

Affiliation

^[1] Univ Sao Paulo, Dept Mech Engn, Sao Paulo - Brazil

^[2] Univ Fed Sao Carlos, Dept Physiotherapy, Rodovia Washington Luis Km 235, BR-13565905 Sao Carlos - Brazil

^[3] Univ Fed Sao Carlos, Nucleus Res Phys Exercise, Dept Physiotherapy, Cardiopulm Physiotherapy Lab, Sao Carlos - Brazil

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF SPORTS MEDICINE; v. 43, n. 01, p. 61-67, JAN 2022.
• Web of Science Citations: 0

Abstract

Healthy aging hemodynamics is known to exhibit a time-dependent loss of function. We aimed at verifying whether older men would have a slowed cardiac output and stroke volume dynamics in response to the onset ({''}on{''}) and on recovery ({''}off{''}) of exercise in comparison to young men. Twenty healthy active men (10 young and 10 older) were recruited. Participants performed an incremental cardiopulmonary exercise testing on a cycle ergometer, and on another day, 3 constant workload tests in different intensities. Compared to younger, older men exhibited a slower cardiac output and stroke volume dynamics in both on and off transients for all exercise intensities (all P < 0.05). During higher intensities, both younger and older men had slower hemodynamic kinetics compared to lower intensities (all P < 0.05). There was strong negative relationship between the time constant of cardiac output on-kinetics during high-intensity with maximal exercise performance in both groups (r = -0.88, P < 0.01). We interpret these findings to mean that healthy older men have slowed hemodynamic kinetics compared to younger, but this difference becomes less evident in higher intensities of exercise. (AU)

• FAPESP's process: 15/26501-1 - Study of limiting factors to physical exercise and adjunct effects to rehabilitation on cardiorespiratory disease: a multicentre approach
• Grantee: Audrey Borghi Silva
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/03524-7 - Engineering design specification analysis through prototypes in a participatory design process of a portable ergometric step
• Grantee: Matheus Borghi Ricardo de Oliveira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 13/06385-1 - Analysis of the kinetic behavior of cardiac output and stroke volume during dynamic exercise at different intensities in healthy elderly and elderly with coronary artery disease
• Grantee: Daniel Augusto dos Santos
• Support Opportunities: Scholarships in Brazil - Scientific Initiation