| Full text | |
| Author(s): |
Total Authors: 3
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| Affiliation: | [1] Univ Fed Rio de Janeiro, BR-21941617 Rio De Janeiro - Brazil
[2] Sao Paulo State Univ, BR-14801930 Araraquara, SP - Brazil
Total Affiliations: 2
|
| Document type: | Journal article |
| Source: | BIOCELL; v. 46, n. 5, p. 1151-1156, 2022. |
| Web of Science Citations: | 0 |
| Abstract | |
It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix (ECM) that may affect cell behaviors. In nature, ECM is a heterogeneous three-dimensional superstructure formed by three major components, glycosaminoglycan, glycoconjugate, and protein, that anchors cellular compartments in tissues and regulates the function and the behavior of cells. Changes in the biointerface alter the quality of ECM and morphology through cell surface receptors, which, in turn, enable it to trigger specific cell signaling and different cellular responses. In fact, a number of strategies have been used to improve the functionality of surfaces and direct cell behavior through precisely designed environments. Herein, we aimed to discuss, through a science-based viewpoint, the biomaterial surface features on cell behavior and analyze the impact of cell physical modification on dental implant development. (AU) | |
| FAPESP's process: | 18/20719-3 - A novel antimicrobial drug-delivery coating for percutaneous implant devices |
| Grantee: | Érica Dorigatti de Avila |
| Support Opportunities: | Research Grants - Young Investigators Grants |