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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

p Implant surface features as key role on cell behavior

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Author(s):
De Molon, Rafael Scaf [1, 2] ; Alves Pereira, Marta Maria [2] ; De Avila, Erica Dorigatti [2]
Total Authors: 3
Affiliation:
[1] Univ Fed Rio de Janeiro, BR-21941617 Rio De Janeiro - Brazil
[2] Sao Paulo State Univ, BR-14801930 Araraquara, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: BIOCELL; v. 46, n. 5, p. 1151-1156, 2022.
Web of Science Citations: 0
Abstract

It has been recognized that physical and chemical properties of biomaterial surfaces mediate the quality of extracellular matrix (ECM) that may affect cell behaviors. In nature, ECM is a heterogeneous three-dimensional superstructure formed by three major components, glycosaminoglycan, glycoconjugate, and protein, that anchors cellular compartments in tissues and regulates the function and the behavior of cells. Changes in the biointerface alter the quality of ECM and morphology through cell surface receptors, which, in turn, enable it to trigger specific cell signaling and different cellular responses. In fact, a number of strategies have been used to improve the functionality of surfaces and direct cell behavior through precisely designed environments. Herein, we aimed to discuss, through a science-based viewpoint, the biomaterial surface features on cell behavior and analyze the impact of cell physical modification on dental implant development. (AU)

FAPESP's process: 18/20719-3 - A novel antimicrobial drug-delivery coating for percutaneous implant devices
Grantee:Érica Dorigatti de Avila
Support Opportunities: Research Grants - Young Investigators Grants