| Full text | |
| Author(s): |
Leidiane Adriano
[1]
;
Etiene Lorriane de Souza Persona
[2]
;
Isvander Gustavo de Souza Persona
[3]
;
Regina Celia Nucci Pontelli
[4]
;
Eduardo M. Rocha
[5]
Total Authors: 5
|
| Affiliation: | [1] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
[2] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
[3] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
[4] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
[5] Universidade de São Paulo. Faculdade de Medicina de Ribeirão Preto. Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço - Brasil
Total Affiliations: 5
|
| Document type: | Journal article |
| Source: | Arquivos Brasileiros de Oftalmologia; v. 85, n. 2, p. 136-143, 2021-08-18. |
| Abstract | |
ABSTRACT Objective: To estimate the epidemiology of the pterygium and its correlation with dry eye symptoms and with the potential systemic and ocular predictors. Methods: This study is a population-based, cross-sectional study in which random visits were made to the 600 households of 600 participants of age ≥40 years in Ribeirão Preto-SP (n=420) and Cassia dos Coqueiros-SP (n=180) in Brazil. The participants were subjected to a structured interview with a detailed questionnaire to collect information on demography and the potential risk factors. Next, random participants with pterygium (n=63) or not (n=110) were evaluated for the ocular surface changes. Results: The frequency of pterygium in Ribeirão Preto was 21% (15.7% among women and 32.1% among men; p=0.0002). In Cássia dos Coqueiros, the corresponding frequency was 19.4% (17.3% among women and 25.5% among men; p=0.28). The mean age of the affected individuals was higher than that of the unaffected ones (65.6 ± 10.5 years vs. 61.2 ± 12.0 years, p=0.02). A positive correlation was noted between pterygium and any prior radiotherapy and chemotherapy (p<0.0001, for both). A higher score on corneal fluorescein and conjunctival lissamine green staining was asso ciated with pterygium (p=0.0003 and 0.0001, respectively). Conclusion: We noted a high frequency of pterygium in two Brazilian adult populations, mainly among the men and elderly. Ocular surface damage and a previous history of radiotherapy and/or chemotherapy were found to be associated with pterygium. (AU) | |
| FAPESP's process: | 14/22451-7 - Sustained drug delivery systems targeting the epithelial tissue |
| Grantee: | Renata Fonseca Vianna Lopez |
| Support Opportunities: | Research Projects - Thematic Grants |