Speciomics as a concept involving chemical speciation and omics

Author(s)

Arruda, Marco Aurelio Zezzi ; Jesus, Jemmyson Romario de ; Blindauer, Claudia Andrea ; Stewart, Alan James

• Document type: Journal article
• Source: JOURNAL OF PROTEOMICS; v. 263, p. 8-pg., 2022-07-15.

Abstract

The study of chemical speciation and the refinement and expansion of omics-based methods are both consolidated and highly active research fields. Although well established, such fields are extremely dynamic and are driven by the emergence of new strategies and improvements in instrumentation. In the case of omics-based studies, subareas including lipidomics, proteomics, metallomics, metabolomics and foodomics have emerged. Here, speciomics is being proposed as an "umbrella" term, that incorporates all of these subareas, to capture studies where the evaluation of chemical species is carried out using omics approaches. This paper contextualizes both speciomics and the speciome, and reviews omics applications used for species identification through examination of proteins, metalloproteins, metabolites, and nucleic acids. In addition, some implications from such studies and a perspective for future development of this area are provided.Significance: The synergic effect between chemical speciation and omics is highlighted in this work, demonstrating an emerging area of research with a multitude of possibilities in terms of applications and further developments. This work not only defines and contextualizes speciomics and individual speciomes, but also demonstrates with some examples the great potential of this new interdisciplinary area of research. (AU)

• FAPESP's process: 20/08543-7 - A speciomic toolkit to investigate fatty acid-mediated changes in plasma zinc speciation and their physiological effects
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Regular Research Grants
• FAPESP's process: 19/00018-3 - Study of inert supports as solid matrix for the quantification of Zn and Cu in tree rings and speleothems using LA-ICP-MS
• Grantee: Pedro dos Santos Moreau
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 18/25207-0 - Nanometallomics applied to soybean cultivation for studying the effects of metal-related nanoparticles
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 14/50867-3 - INCT 2014: National Institute of Science and Technology in Bioanalysis
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 17/50085-3 - PIRE: climate research education in the Americas using tree-ring speleothem examples (PIRE-CREATE)
• Grantee: Francisco William da Cruz Junior
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 19/24445-8 - EMU granted in process 2018/25207-0: inductively coupled plasma mass spectrometer
• Grantee: Marco Aurelio Zezzi Arruda
• Support Opportunities: Multi-user Equipment Program