Comparative omics through hyphenated techniques focusing on metal complexes in tra...
| Grant number: | 18/25207-0 |
| Support type: | Research Projects - Thematic Grants |
| Duration: | October 01, 2019 - September 30, 2024 |
| Field of knowledge: | Physical Sciences and Mathematics - Chemistry |
| Principal Investigator: | Marco Aurelio Zezzi Arruda |
| Grantee: | Marco Aurelio Zezzi Arruda |
| Home Institution: | Instituto de Química (IQ). Universidade Estadual de Campinas (UNICAMP). Campinas , SP, Brazil |
| Co-Principal Investigators: | Ricardo Antunes de Azevedo |
| Assoc. researchers: | Claudio Francisco Tormena ; Italo Odone Mazali |
Abstract
Different areas of production, such as food, agricultural and technological demand for products based on nanotechnology. This fact alerts the community about the possible effects that products composed of nanoparticles (NPs) can cause to the environment and, consequently, to living organisms. NPs may be present in biological systems and linked to molecules performing different functions on organisms and cells. Due to their high surface-volume ratio, NPs are highly reactive and catalytic, and can pass through cell membranes. However, their interactions with such systems are not yet well known. Despite this, some studies have warned about the possible effects of NPs, when in contact with some living organisms. In Brazil, there is no law that determines the permissible concentration of these in foods, as well as the discarding of NPs in the environment. In this way, through metallomics and other omics platforms, this project focus on the evaluation of the biological effects of the soybean plants, cultivated in the presence of silver, copper and silica nanoparticles, through macro characteristics of the plants, as growth, wet mass, germination rate, and others, as well as possible changes in terms of (metallo)proteins, lipids, enzymes and metals under the influence, or not, of NPs. (AU)