Pandemic Clones of CTX-M-15 Producing Klebsiella pneumoniae ST15, ST147, and ST307 in Companion Parrots

Author(s)

Davies, Yame Miniero ; Vieira Cunha, Marcos Paulo ; Dropa, Milena ; Lincopan, Nilton ; Moura Gomes, Vasco Tulio ; Moreno, Luisa Zanoli ; Zanoli Sato, Maria Ines ; Moreno, Andrea Micke ; Knobl, Terezinha

• Document type: Journal article
• Source: MICROORGANISMS; v. 10, n. 7, p. 9-pg., 2022-07-01.

Abstract

Psittacine birds are commonly kept as companion birds and the maintenance of these birds in captivity may represent a zoonotic risk and contribute to the propagation of multidrug-resistant and beta-lactamase extended-spectrum (ESBLs)-producing pathogens. This study aimed to identify and characterize strains of the Klebsiella pneumoniae complex isolated from diseased psittacine birds, determining virulence and resistance profiles. K. pneumoniae strains were isolated from 16 birds (16/46). All strains carried more than three virulence genes, with a high frequency of fimH and kpn (93.75%), uge (87.52%), and irp-2 (81.25%) genes. The antimicrobial susceptibility revealed that 3/16 strains were ESBL producers. Genomic analysis revealed that CTX-M-15-positive strains belonged to sequence types (STs) ST15, ST147, and ST307, characterized as international clones associated with outbreaks of healthcare-associated infections (HAIs) worldwide. (AU)

• FAPESP's process: 16/12641-9 - Antimicrobial Resistance of Escherichia coli isolated from broilers raised in conventional and organic poultry farms.
• Grantee: Terezinha Knöbl
• Support Opportunities: Regular Research Grants