Oral Teratoma with Hairy Polyp-Like Features: A Brief Report of a Rare Presentation

Author(s)

Scarini, Joao Figueira ; de Lima-Souza, Reydson Alcides ; Lavareze, Luccas ; Emerick, Carolina ; Miyaok, Rafaella Dini ; Schiavon Kinasz, Leticia Raysa ; Maunsell, Rebecca ; Abu Egal, Erika Said ; Altemani, Albina ; Mariano, Fernanda Viviane

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY; v. N/A, p. 4-pg., 2022-11-03.

Abstract

We present a 21-day-old female child presenting with a large oral epithelialized tumor implanted at the rhinopharynx and ethmoid plate through a cleft palate, associated with feeding and respiratory difficulties. The histopathological exam showed mature central adipose tissue, hair follicles, sebaceous glands, and neurovascular structures, lined by keratinized stratified squamous epithelium. Proliferative cartilaginous, glandular, lymphatic, bony, and immature myxoid tissue was seen at the posterior region and insertion. Despite the characterization of the tumor as a teratoma containing structures derived from the three embryonic leaflets, the anterior portion presented a microscopic bigeminal pattern fully compatible with hairy polyp. (AU)

• FAPESP's process: 21/12567-1 - Validation of potential genomic alterations found during the malignant transformation of the pleomorphic adenoma
• Grantee: João Figueira Scarini
• Support Opportunities: Scholarships abroad - Research Internship - Doctorate
• FAPESP's process: 15/07304-0 - Study of genetic and metabolic changes of pleomorphic adenoma and carcinoma ex pleomorphic adenoma by exome, gene expression and immunohistochemistry
• Grantee: Fernanda Viviane Mariano Brum Corrêa
• Support Opportunities: Research Grants - Young Investigators Grants
• FAPESP's process: 19/09419-0 - Genomic alterations in the malignant transformation of the Pleomorphic Adenoma
• Grantee: João Figueira Scarini
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/06809-2 - Analysis of mass spectrometry in the malignant transformation of the pleomorphic adenoma. correlation of data with gene expression and exome
• Grantee: Reydson Alcides de Lima Souza
• Support Opportunities: Scholarships in Brazil - Master