| Full text | |
| Author(s): Show less - |
Campos, Angelica Cristine de Almeida
;
Cicolo, Sofia
;
de Oliveira, Cairo Monteiro
;
Molina, Camila Vieira
;
Navas-Suarez, Pedro Enrique
;
dos Santos, Thais Poltronieri
;
da Silveira, Vanessa Barbosa
;
Barbosa, Carla Meneguin
;
Baccarin, Raquel Yvonne Arantes
;
Durigon, Edison Luiz
;
Goes, Luiz Gustavo Bentim
;
Belli, Carla Bargi
;
Oliveira, Danielle Bruna Leal
Total Authors: 13
|
| Document type: | Journal article |
| Source: | Brazilian Journal of Microbiology; v. N/A, p. 7-pg., 2023-01-27. |
| Abstract | |
BackgroundEquid herpesvirus (EHV) commonly affects horses causing neurologic and respiratory symptoms beside spontaneous abortions, meaning huge economic losses for equine industry worldwide. In foals, the virus can facilitate secondary infections by Rhodococcus equi, important in morbidity and mortality in equines. A total of five genotypes of EHV were previously described in Brazil including EHV-1, EHV-2, EHV-3, EHV-4, and EHV-5. EHV-2 genotype had only been previously described in Brazil in asymptomatic animals. We report the investigation of the dead of 11 foals in Middle-west region of Brazil showing respiratory and neurological symptoms, as well as several abortions in mares from the same farm.MethodsClinical and laboratory exams were performed in this case study. Lung, whole blood, serum, and plasma samples were analyzed by necroscopic and histopathologic techniques followed by molecular assays (conventional and qPCR and Sanger sequencing).Results and conclusionLaboratory exams revealed neutrophilia leukocytosis. Necroscopic and histopathologic findings were suppurative bronchopneumonia and ulcerative enteritis. Molecular assays point to the absence of the bacteria Rhodococcus equi and other viruses (including other EHV). The presence of EHV-2 DNA was confirmed by sequencing in serum sample from one foal. This is the first confirmed outbreak of EHV-2 causing disease in Brazilian horses with confirmed presence of the virus, and which highlight the important role of EHV-2 in equine respiratory disease and spontaneous abortions in equid in Brazil. (AU) | |
| FAPESP's process: | 18/05346-6 - Development of specific serological tests from recombinant antigens derived from ZIKV |
| Grantee: | Vanessa Barbosa da Silveira |
| Support Opportunities: | Scholarships in Brazil - Technical Training Program - Technical Training |
| FAPESP's process: | 16/08727-5 - Development of serological assay for Zika virus IgG and IgM based on low coast ELISA |
| Grantee: | Danielle Bruna Leal de Oliveira |
| Support Opportunities: | Research Grants - Innovative Research in Small Business - PIPE |
| FAPESP's process: | 14/15090-8 - Monitoring of influenza virus in bats from tropical and sub tropical region of Brazil |
| Grantee: | Angélica Cristine Góes de Almeida Campos |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 20/01487-4 - Survey of respiratory viruses (Influenza, Paramyxovirus, Coronavirus and Bocavirus) in captive and wild nonhuman primates from metropolitan area of São Paulo city |
| Grantee: | Camila Vieira Molina |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 18/18867-4 - Monitoring and molecular characterization of arboviros isolated from dippers of the Brazilian west Amazon (State of Rondônia) |
| Grantee: | Cairo Monteiro de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Master |