Older Women Who Practiced Physical Exercises before the COVID-19 Pandemic Present Metabolic Alterations and Worsened Functional Physical Capacity after One Year of Social Isolation

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Cezario, Kizzy ; Freitas dos Santos, Carlos Andre ; Almada Filho, Clineu de Mello ; Amirato, Gislene Rocha ; da Paixao, Vitoria ; Almeida, Ewin Barbosa ; do Amaral, Jonatas Bussador ; Caldo-Silva, Adriana ; Pimenta, Nuno ; Sampaio, Antonio Rodrigues ; Teques, Pedro ; Rodrigues, Fernanda Monteiro ; Franca, Carolina Nunes ; Lacerda Bachi, Andre Luis

• Document type: Journal article
• Source: HEALTHCARE; v. 10, n. 9, p. 14-pg., 2022-09-01.

Abstract

Background: Because the consequences of the lifestyle changes in older adults associated with the social isolation imposed in response to the COVID-19 pandemic are not fully understood, here, we investigated the effects of one year of social isolation imposed by COVID-19 on the metabolic parameters and functional physical capacity of older women who regularly practiced physical exercises before the pandemic. Methods: Systemic lipid and protein profiles, estimated creatinine clearance (ECC), and functional physical capacity (FPC) were assessed before (January-February 2020) and 12 months after social isolation in 30 older women (mean age 73.77 +/- 6.22) who were engaged in a combined-exercise training program for at least 3 years before the COVID-19 pandemic. Results: In this group, we observed increased plasma levels of triglycerides and creatinine, an increase in the time necessary to perform gait speed and time-up-and-go tests, and reduced muscle strength assessed by the handgrip test and ECC post-COVID-19 pandemic relative to values recorded pre-pandemic. In addition, we observed significant correlations (both negative and positive) between anthropometric, some metabolic parameters, and physical tests. Conclusion: One year of interruption of physical exercise practice imposed in response to the COVID-19 pandemic significantly altered some systemic metabolic parameters and worsened ECC and FPC in older women. (AU)

• FAPESP's process: 19/13094-0 - Evaluation of the influence of combined physical exercise and L-glutamine supplementation on the inflammatory profile and response of specific antibodies to the vaccine against the influenza virus in elderly people
• Grantee: Fernanda Rodrigues Monteiro
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 19/14115-0 - Influence of L-glutamine supplementation in the sarcopenia and immune/inflammatory response both systemic and in the respiratory tract of elderly practitioners or not of a regular program of combined physical exercises submitted to Influenza virus vaccine
• Grantee: André Luis Lacerda Bachi
• Support Opportunities: Regular Research Grants
• FAPESP's process: 19/13188-4 - Study of the effects of glutamine supplementation on the immunophenotyping and activation profile of t and b lymphocytes from practicing or NON-EXERCISING seniors submitted to influenza virus vaccination
• Grantee: Tamaris Roseira dos Reis Pavao
• Support Opportunities: Scholarships in Brazil - Scientific Initiation