Healing status of burn wound healing: ATR-FTIR study

Author(s)

Castro, Pedro ; Zorn, Telma ; Zezell, Denise ; IEEE

• Document type: Journal article
• Source: 2021 SBFOTON INTERNATIONAL OPTICS AND PHOTONICS CONFERENCE (SBFOTON IOPC); v. N/A, p. 3-pg., 2021-01-01.

Abstract

The purpose of this study is to use infrared spectroscopy (FTIR) for monitoring biological changes in burned skin. Wistar rats dorsum samples were compared to healthy group samples at 7, 14, 21 days after burn. Proteins changes of burn wounds were monitored by area under the curve (AUC) of bands at 1630 cm(-1), 1543 cm(-1) and 1743 cm(-1). Kruskal Wallis normality tests, unpaired t test with Welch's correction were used to evaluate the differences between AUC. These bands suggest association between collagen activity during wound healing stages. Our result indicates progressive recovery of 7,14 and 21 days tissues when compared with the healthy group. (AU)

• FAPESP's process: 05/51689-2 - Optics and Photonics Research Center at UNICAMP
• Grantee: Hugo Luis Fragnito
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC