| Full text | |
| Author(s): |
Protachevicz, Paulo R.
;
Borges, Fernando S.
;
Iarosz, Kelly C.
;
Baptista, Murilo S.
;
Lameu, Ewandson L.
;
Hansen, Matheus
;
Caldas, Ibere L.
;
Szezech, Jose D., Jr.
;
Batista, Antonio M.
;
Kurths, Juergen
Total Authors: 10
|
| Document type: | Journal article |
| Source: | FRONTIERS IN PHYSIOLOGY; v. 11, p. 9-pg., 2020-09-03. |
| Abstract | |
In the brain, the excitation-inhibition balance prevents abnormal synchronous behavior. However, known synaptic conductance intensity can be insufficient to account for the undesired synchronization. Due to this fact, we consider time delay in excitatory and inhibitory conductances and study its effect on the neuronal synchronization. In this work, we build a neuronal network composed of adaptive integrate-and-fire neurons coupled by means of delayed conductances. We observe that the time delay in the excitatory and inhibitory conductivities can alter both the state of the collective behavior (synchronous or desynchronous) and its type (spike or burst). For the weak coupling regime, we find that synchronization appears associated with neurons behaving with extremes highest and lowest mean firing frequency, in contrast to when desynchronization is present when neurons do not exhibit extreme values for the firing frequency. Synchronization can also be characterized by neurons presenting either the highest or the lowest levels in the mean synaptic current. For the strong coupling, synchronous burst activities can occur for delays in the inhibitory conductivity. For approximately equal-length delays in the excitatory and inhibitory conductances, desynchronous spikes activities are identified for both weak and strong coupling regimes. Therefore, our results show that not only the conductance intensity, but also short delays in the inhibitory conductance are relevant to avoid abnormal neuronal synchronization. (AU) | |
| FAPESP's process: | 15/50122-0 - Dynamic phenomena in complex networks: basics and applications |
| Grantee: | Elbert Einstein Nehrer Macau |
| Support Opportunities: | Research Projects - Thematic Grants |
| FAPESP's process: | 20/04624-2 - Synaptic plasticity in neuronal networks |
| Grantee: | Paulo Ricardo Protachevicz |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 15/07311-7 - Dynamic behaviour of neural networks |
| Grantee: | Kelly Cristiane Iarosz |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 16/23398-8 - Synaptic plasticity in neuronal networks with time delay |
| Grantee: | Ewandson Luiz Lameu |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 17/18977-1 - Analysis of Electrical Synapses Contribution in Neuronal Synchronization |
| Grantee: | Fernando da Silva Borges |
| Support Opportunities: | Scholarships in Brazil - Post-Doctoral |
| FAPESP's process: | 18/03211-6 - Non linear dynamics |
| Grantee: | Iberê Luiz Caldas |
| Support Opportunities: | Research Projects - Thematic Grants |