| Full text | |
| Author(s): |
Andreo, Lucas
;
Ribeiro, Beatriz G.
;
Alves, Agnelo N.
;
Martinelli, Andreia S. A.
;
Soldera, Carla B.
;
Horliana, Anna Carolina R. T.
;
Bussadori, Sandra Kalil
;
Fernandes, Kristianne P. S.
;
Mesquita-Ferrari, Raquel A.
Total Authors: 9
|
| Document type: | Journal article |
| Source: | Photochemistry and Photobiology; v. 96, n. 5, p. 9-pg., 2020-04-23. |
| Abstract | |
Peripheral nerve injury (PNI) can lead to sensory and/or motor impairment. As a treatment photobiomodulation (PBM) has demonstrated positive effects in terms of the maintenance of muscle activation and trophism. Wistar rats were divided into five groups: control, injury, injury + PBMn (irradiation over injured nerve), injury + PBMm (irradiation over affected muscle) and injury + PBMnm (irradiation over nerve and muscle). The left sciatic nerve was submitted to a crushing injury. Treatment was administered with low-level laser (780 nm, 0.04 cm(2), 1 W cm(-2), 3.2 J) over the injured nerve and/or the tibialis anterior muscle. The effects of PBM were favorable on muscle morphology and gene expression of calcineurin, myogenin and acetylcholine receptors. PBM led to an acceleration on muscle repair process, and effects were more evident in 2 weeks after PNI. Thus, PBM is indicated for the area over both the injured nerve and the affected muscle. (AU) | |
| FAPESP's process: | 14/12381-1 - Comparative analysis of the effect of previous laser therapy associated or not to post treatment on the modulation of inflammatory cytokines, oxidative stress and the determination of muscle fiber type after acute injury |
| Grantee: | Raquel Agnelli Mesquita Ferrari |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 13/07502-1 - Effect of laser therapy on gene expression and production of cytokines, chemokines and growth factors involved in muscle repair |
| Grantee: | Kristianne Porta Santos Fernandes |
| Support Opportunities: | Regular Research Grants |