Short sleep duration increases salivary IL-6 production

Author(s)

Reinhardt, Erica Lui ; Fernandes, Pedro A. C. M. ; Markus, Regina P. ; Fischer, Frida Marina

• Document type: Journal article
• Source: CHRONOBIOLOGY INTERNATIONAL; v. 33, n. 6, p. 3-pg., 2016-01-01.

Abstract

Morning shift sleep restriction has been associated with higher plasma IL-6 levels. The aim of this study was to investigate the effect of sleep duration on salivary IL-6. Sleep duration of morning shift workers was estimated by actigraphy. Workers with "longer sleep duration" (LSD; N = 6) and "shorter sleep duration" (SSD; N = 15) were then compared regarding salivary IL-6 levels determined at 14:00 h, bed and wake times. SSD workers did not show daily variation of IL-6 and presented higher levels at bedtime and 14:00 h compared to LSD workers. In this study, SSD is associated with an increase in salivary IL-6 content. (AU)

• FAPESP's process: 11/10503-4 - Assessment of effects of night work in the levels of inflammatory cytokines, melatonin and cortisol in saliva
• Grantee: Frida Marina Fischer
• Support Opportunities: Regular Research Grants