Ecotoxicological risk assessment of the "Acid Black 210" dye

Author(s)

Rocha, Otavio Pelegrino ; Cesila, Cibele Aparecida ; Christovam, Elisa Maria ; de Moraes Barros, Silvia Berlanga ; Boldrin Zanoni, Maria Valnice ; de Oliveira, Danielle Palma

• Document type: Journal article
• Source: Toxicology; v. 376, p. 7-pg., 2017-02-01.

Abstract

The "Acid Black 210" dye is one of the most used black dyes by the leather industry. This compound contains three azo groups in its chemical structure, and has been quoted as a non-regulated dye with toxicological concern, since it could generate carcinogenic aromatic amines. The objective of this study was to perform the ecotoxicological risk assessment of this dye through testing its toxicity in vitro and in vivo with the Ames test, the Comet assay, the Daphnia similis test, and the zebrafish embryo acute toxicity test. Moreover, we evaluated the presence of this dye in environmental samples related with a tannery industry. All the tests performed were negative, with the exception of the Ames test with the Salmonella typhimurium TA98 strain, which resulted in a low mutagenic potency. Due to the low concentrations of the "Acid Black 210" dye found in tannery effluents, and the high concentrations where any toxic activity is occasionally described, we concluded that this dye is safe from the ecotoxicological point of view in the areas evaluated and in the light of the current knowledge. (C) 2016 Elsevier Ireland Ltd. All rights reserved. (AU)

• FAPESP's process: 08/10449-7 - Assessment of occurrence, toxicity/genotoxicity and degradation processes of dyes in effluents and surface water
• Grantee: Maria Valnice Boldrin
• Support Opportunities: Research Projects - Thematic Grants
• FAPESP's process: 13/09317-7 - Assessment of the ecogenotoxicologic risk of using textile dyes.
• Grantee: Otávio Pelegrino Rocha
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 13/06172-8 - Evaluation of the mutagenic potential of textile dyes using the micronucleus assay
• Grantee: Cibele Aparecida Cesila
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 13/24340-5 - Development and validation of method for determining of dye acid black 210 by LC-ESI-MS/MS in wastewater of tanning and evaluation of genotoxicity
• Grantee: Elisa Maria Christovam
• Support Opportunities: Scholarships in Brazil - Scientific Initiation