Advanced search
Start date
Betweenand

Occurrence, genotoxicity and ecotoxicological risk of dyes in the aquatic environment

Grant number: 12/13344-7
Support type:Scholarships in Brazil - Doctorate
Effective date (Start): October 01, 2012
Effective date (End): May 31, 2016
Field of knowledge:Biological Sciences - Pharmacology - Toxicology
Principal Investigator:Gisela de Aragão Umbuzeiro
Grantee:Francine Inforçato Vacchi
Home Institution: Faculdade de Ciências Farmacêuticas (FCF). Universidade de São Paulo (USP). São Paulo , SP, Brazil
Associated research grant:08/10449-7 - Assessment of occurrence, toxicity/genotoxicity and degradation processes of dyes in effluents and surface water, AP.TEM
Associated scholarship(s):13/22345-0 - Genotoxicity assessment of disperse red 1 dye in aquatic species using fish cell lines, BE.EP.DR

Abstract

Dyes are used in the coloration of different substrates, including paper, leather andplastics, but the most important use is on textiles and 10 to 15% of these dyes might belost into the environment. Azo dyes are the most important class, accounting for over50% of all commercial dyes, and this class has been the most studied. In general azodyes are toxic to aquatic organisms and some types of dyes are more toxic than others.But although these compounds as well as their reduced/chlorinated transformationproducts can be found in aquatic ecosystems, no mutagenicity data are available untilnow in aquatic organisms. This remark remains of value, as well, regarding genotoxicitypotential of such dyes towards aquatic organisms. Many studies have demonstrated thatDNA damage measurement represents a very sensitive biomarker of exposure in aquaticspecies that can be studied both in vivo and in vitro using for example fish cell lines.The aim of this project is to bring some informations regarding the monitoring in SaoPaulo State aquatic ecosystems of Disperse Red 1 dye suspected to impact aquatic life;and regarding the assessment of genotoxicity using both in vitro (fish cell lines) and invivo in fish exposed to dye effluents in the field.

Scientific publications
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
VACCHI, FRANCINE INFORCATO; DE SOUZA VENDEMIATTI, JOSIANE APARECIDA; DA SILVA, BIANCA FERREIRA; BOLDRIN ZANONI, MARIA VALNICE; UMBUZEIRO, GISELA DE ARAGAO. Quantifying the contribution of dyes to the mutagenicity of waters under the influence of textile activities. Science of The Total Environment, v. 601, p. 230-236, DEC 1 2017. Web of Science Citations: 18.
VACCHI, FRANCINE INFORCATO; VON DER OHE, PETER CARSTEN; DE ALBUQUERQUE, ANJAINA FERNANDES; DE SOUZA VENDEMIATTI, JOSIANE APARECIDA; JESUS AZEVEDO, CARINA CRISTINA; HONORIO, JAQUELINE GONCALVES; DA SILVA, BIANCA FERREIRA; BOLDRIN ZANONI, MARIA VALNICE; HENRY, THEODORE B.; NOGUEIRA, ANTONIO J.; UMBUZEIRO, GISELA DE ARAGADO. Occurrence and risk assessment of an azo dye - The case of Disperse Red 1. Chemosphere, v. 156, p. 95-100, AUG 2016. Web of Science Citations: 12.

Please report errors in scientific publications list by writing to: cdi@fapesp.br.