ToxBioColour - Toxicology of Bio-based Colourants for a Sustainable Environment

• Grant number: 20/04628-8
• Support Opportunities: Regular Research Grants
• Start date: November 01, 2020
• End date: October 31, 2022
• Field of knowledge: Biological Sciences - Genetics - Mutagenesis
• Principal Investigator: Gisela de Aragão Umbuzeiro
• Grantee: Gisela de Aragão Umbuzeiro
• Host Institution: Faculdade de Tecnologia (FT). Universidade Estadual de Campinas (UNICAMP). Limeira , SP, Brazil
• City of the host institution: Limeira
• Associated researchers: Riikka Räisänen

Abstract

Synthetic dyes and pigments are widely used in the textile industry, and the potential risks of colourants such as azo dyes to human health and the environment are already recognized. Certain natural compounds have a long history as colourants but after the 20th century transition to synthetic dyes, their usage in textile coloration has been minimal. There is a trend in the world to produce sustainable materials, but the possibility of using natural dyes to help achieve this vision has not been properly explored. This fact motivated the BioColour project to design and develop novel sustainable products with the aid of environmentally sound natural colourants. The BioColour (Bio-based Dyes and Pigments for Colour Palette, https://biocolour.fi/), is a consortium recently approved by the Academy of Finland (https://www.aka.fi/en). The Laboratory of Ecotoxicoloy and Genotoxicity (LAEG) from UNICAMP is participating in the Work Package WP3 (Toxicological safety assessment of biocolourants) component of the BioColour project, performing acute toxicity testing with Daphnia and in vitro mutagenicity assays of natural dyes. The objective of the proposed ToxBioColour project is to provide an in-depth toxicological characterization of the most promising natural dyes selected by the BioColour consortium and the effluents from simulated dyeing process. These studies will use different aquatic models (algae and fish) to verify acute and chronic toxicity including in vivo genotoxicity evaluations (comet assay in fish). We expect the outcome to be a family of environmentally friendly natural dyes for traditional and waterless dyeing technologies. (AU)

Scientific publications

(7)

(The scientific publications listed on this page originate from the Web of Science or SciELO databases. Their authors have cited FAPESP grant or fellowship project numbers awarded to Principal Investigators or Fellowship Recipients, whether or not they are among the authors. This information is collected automatically and retrieved directly from those bibliometric databases.)

MAGALHAES, GABRIEL RAMPAZZO; MILITAO, GABRIELY FERNANDA GROTO; DE FARIAS, NATALIA OLIVEIRA; DE ALBUQUERQUE, ANJAINA FERNANDES; BOTELHO, MARINA TENORIO; RAISANEN, RIIKKA; FREEMAN, HAROLD S.; DE ARAGAO UMBUZEIRO, GISELA. Acryloyl esters of emodin for waterless dyeing and toxicological studies. COLORATION TECHNOLOGY, v. N/A, p. 9-pg., 2023-10-12. (22/04482-9, 21/06369-2, 20/04628-8)

HERRALA, MIKKO; YLI-OYRA, JOHANNA; DE ALBUQUERQUE, ANJAINA FERNANDES; DE FARIAS, NATALIA OLIVEIRA; MORALES, DANIEL ALEXANDRE; RAISANEN, RIIKKA; FREEMAN, HAROLD S.; UMBUZEIRO, GISELA ARAGAO; RYSA, JAANA. Waterless Dyeing and In Vitro Toxicological Properties of Biocolorants from Cortinarius sanguineus. JOURNAL OF FUNGI, v. 8, n. 11, p. 16-pg., 2022-11-01. (20/04628-8)

BOTELHO, MARINA TENORIO; MILITAO, GABRIELY GROTO; BRINKMANN, MARKUS; UMBUZEIRO, GISELA DE ARAGAO. Toxicity and mutagenicity studies of 6PPD-quinone in a marine invertebrate species and bacteria. Environmental and Molecular Mutagenesis, v. 64, n. 6, p. 7-pg., 2023-07-17. (20/04628-8, 22/04482-9)

DE FARIAS, NATALIA OLIVEIRA; RODRIGUES, AMANDA ROCHA; BOTELHO, MARINA TENORIO; MAGALHAES, GABRIEL RAMPAZZO; RAISANEN, RIIKKA; FREEMAN, HAROLD S.; UMBUZEIRO, GISELA DE ARAGAO. The natural anthraquinone dye emodin: Eco/genotoxicological characterization for aquatic organisms. Food and Chemical Toxicology, v. 189, p. 8-pg., 2024-05-22. (20/04628-8, 21/06369-2, 23/07768-3, 22/04482-9)

BOTELHO, MARINA TENORIO; UMBUZEIRO, GISELA DE ARAGA. Designing and applying a methodology to assess sperm cell viability and DNA damage in a model amphipod. Science of The Total Environment, v. 950, p. 11-pg., 2024-08-09. (22/04482-9, 20/04628-8)

DE FARIAS, NATALIA OLIVEIRA; PIRES, MARTA SIVIERO GUILHERME; MOREIRA, BRUNA DE JESUS; DOS SANTOS, AMANDA; FREEMAN, HAROLD STANLEY; TOUKOLA, PEPPI; DE ALBUQUERQUE, ANJAINA FERNANDES; RAISANEN, RIIKKA; UMBUZEIRO, GISELA DE ARAGAO. Natural indigo toxicity for aquatic and terrestrial organisms. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, v. 290, p. 9-pg., 2024-12-28. (20/04628-8)

MUSSAGY, CASSAMO U.; DOS SANTOS, AMANDA; MILITAO, GABRIELY F. G.; DE OLIVEIRA, JESSICA CAROLINA SILVA; UMBUZEIRO, GISELA DE A.; PEIXOTO, GUILHERME; PESSOA JR, ADALBERTO; SANTOS-EBINUMA, VALERIA C.. Phaffia rhodozyma biorefinery: A sustainable pathway to obtain natural pigments and production of methane biogas as renewable fuel. CHEMICAL ENGINEERING JOURNAL, v. 473, p. 12-pg., 2023-10-01. (21/06686-8, 20/08655-0, 19/15493-9, 20/04628-8)