Extraction of Flavonoids From Natural Sources Using Modern Techniques

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Chaves, Jaisa Oliveira ; de Souza, Mariana Correa ; da Silva, Laise Capelasso ; Lachos-Perez, Daniel ; Torres-Mayanga, Paulo Cesar ; Machado, Ana Paula da Fonseca ; Forster-Carneiro, Tania ; Vazquez-Espinosa, Mercedes ; Gonzalez-de-Peredo, Ana Velasco ; Barbero, Gerardo Fernandez ; Rostagno, Mauricio Ariel

• Document type: Journal article
• Source: RONTIERS IN CHEMISTR; v. 8, p. 25-pg., 2020-09-25.

Abstract

Flavonoids are one of the main groups of polyphenols found in natural products. Traditional flavonoid extraction techniques are being replaced by advanced techniques to reduce energy and solvent consumption, increase efficiency and selectivity, to meet increased market demand and environmental regulations. Advanced technologies, such as microwaves, ultrasound, pressurized liquids, supercritical fluids, and electric fields, are alternatives currently being used. These modern techniques are generally faster, more environmentally friendly, and with higher automation levels compared to conventional extraction techniques. This review will discuss the different methods available for flavonoid extraction from natural sources and the main parameters involved (temperature, solvent, sample quantity, extraction time, among others). Recent trends and their industrial importance are also discussed in detail, providing insight into their potential. Thus, this paper seeks to review the innovations of compound extraction techniques, presenting in each of them their advantages and disadvantages, trying to offer a broader scope in the understanding of flavonoid extraction from different plant matrices. (AU)

• FAPESP's process: 18/17089-8 - Separation of bioactive compounds from black tea and mate by on-line coupling of pressurized liquid extraction with an adsorbent and evaluation of their antimicrobial potential
• Grantee: Mariana Corrêa de Souza
• Support Opportunities: Scholarships in Brazil - Doctorate (Direct)
• FAPESP's process: 18/05999-0 - Waste2energy: integration of the supercritical and anaerobic digestion technologies for the management of water and food waste
• Grantee: Tânia Forster Carneiro
• Support Opportunities: Regular Research Grants
• FAPESP's process: 18/14582-5 - Development of a two-dimensional extraction, separation and analysis system for evaluating the bioactivity of phytochemicals
• Grantee: Maurício Ariel Rostagno
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2
• FAPESP's process: 16/19930-6 - Evaluation of the extraction with pressurized liquid assisted by ultrasound coupled to the solid phase extraction for the purification of phenolic compounds from tea (Camellia sinensis)
• Grantee: Mariana Corrêa de Souza
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 18/14938-4 - Waste2energy: integration of supercritical technologies and anaerobic digestion through an automated system for the production of biofuel precursors
• Grantee: Tânia Forster Carneiro
• Support Opportunities: Research Grants - Young Investigators Grants - Phase 2