Proanthocyanidin protects the enamel against initial erosive challenge when applied over acquired pellicle

Author(s)

Boteon, Ana Paula ; Dallavilla, Gabriela Guarda ; Cardoso, Fabricia ; Wang, Linda ; Rios, Daniela ; Honorio, Heitor Marques

• Document type: Journal article
• Source: AMERICAN JOURNAL OF DENTISTRY; v. 33, n. 5, p. 4-pg., 2020-10-01.

Abstract

Purpose: To evaluate the effect of proanthocyanidin applied over acquired pellicle in the inhibition of enamel demineralization, in a short-term erosive challenge. Methods: The acquired pellicle was formed in situ by the placement of intraoral palatal devices in two healthy volunteers for 2 hours. The enamel blocks of each group (n = 16) were treated in vitro according to the following groups: G1: 6.5% proanthocyanidin gel and acquired pellicle formed in situ; G2: only 6.5% proanthocyanidin gel; G3: only acquired pellicle formed in situ; and G4: no intervention (neither gel nor acquired pellicle). Gels were applied for 1 minute. Then, enamel blocks were immersed in 0.5% citric acid, pH 2.5, for 30 seconds to promote a short erosive challenge. The response variable used was the percentage of surface hardness loss (Knoop Hardness Number). Data were analyzed by Kruskal-Wallis and Dunn's test (P< 0.001). Results: Statistical analysis showed that the G1 group presented a statistically significant difference compared to the other groups (P< 0.001), since it showed the lowest values of hardness loss (G1: median= 7.7a; 1 degrees Q= 4.7; 3 degrees Q= 10.3; G2: median= 17.7b; 1 degrees Q= 10.8; 3 degrees Q= 23.4; G3: median- 19.1b; 1 degrees Q= 11.1; 3 degrees Q= 21,1; G4: median= 24.9b; 1 degrees Q= 19.4; 3 degrees Q= 31.9). (AU)

• FAPESP's process: 18/05847-5 - Effect of metalloproteinases inhibitors and/or remineralizing agents on tooth structure submitted to erosion
• Grantee: Heitor Marques Honório
• Support Opportunities: Regular Research Grants