Overview of Pectin-Derived Microparticles through Microfluidic Technology

Author(s)

da Silva, Pedro Brivaldo Viana ; Fabi, Joao Paulo

• Document type: Journal article
• Source: FLUIDS; v. 9, n. 8, p. 19-pg., 2024-08-01.

Abstract

The scientific field of microcarrier systems has gained significant advancements, especially in drug delivery and controlled release mechanisms. This manuscript provides a comprehensive overview of the progress in developing pectin-derived microcarriers fabricated using microfluidic technology. Pectin, a naturally occurring polysaccharide, has garnered attention due to its biocompatibility, biodegradability, and ability to form hydrogels, making it an ideal candidate for forming microcarriers. The integration of microfluidic technology in synthesizing these carriers has revolutionized their design and functionality, enabling precise control over size, morphology, and encapsulation efficiency. This review systematically analyzes the methodologies employed in the microfluidic fabrication of pectin-based microparticles, highlighting the significant advantages this technology offers, such as reduced use of solvents, enhanced reproducibility, and scalability. (AU)

• FAPESP's process: 13/07914-8 - FoRC - Food Research Center
• Grantee: Bernadette Dora Gombossy de Melo Franco
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 22/12834-2 - Effects of modified pectins on gut health: pre-clinical and clinical studies to assess cellular, transcriptional, and epigenetic effects
• Grantee: Joao Paulo Fabi
• Support Opportunities: Regular Research Grants
• FAPESP's process: 22/12270-1 - Study of colonic microbiota modulation through pectin oligomers encapsulated in pectic matrix
• Grantee: Pedro Brivaldo Viana da Silva
• Support Opportunities: Scholarships in Brazil - Doctorate