High-pressure liquid impregnation of barbatimao bark extract into biopolymeric membrane composed of PBS/PLA and Cloisite 20 A blend

Author(s)

Veggi, Priscilla C. ; Hatami, Tahmasb ; Campos, Leonardo F. ; Mazur, Luciana P. ; do Carmo, Luana E. ; Mei, Lucia H. I. ; Vigano, Juliane

• Document type: Journal article
• Source: JOURNAL OF SUPERCRITICAL FLUIDS; v. 216, p. 9-pg., 2025-02-01.

Abstract

Renowned for its medicinal properties, barbatimao bark extract contains bioactive compounds susceptible to degradation, necessitating their safeguarding within a stable matrix for diverse biomedical applications. This study investigates using high-pressure liquid impregnation (HPLI) to load barbatimao extract into biopolymeric membranes at 30, 45, and 60 degrees C, and 11 MPa. HPLI combines the simplicity of direct immersion with improved mass transfer rates under high pressure. Biopolymeric membranes made from poly(butylene succinate) (PBS), poly(lactic acid) (PLA), and Cloisite 20 A (C20A) in a 50/45/5 (v/v) composition were created using electrospinning. Comparative analysis with conventional methods, along with evaluation of impregnated membrane properties using SEM, FTIR, and thermogravimetric analysis, demonstrated the effectiveness of HPLI. HPLI yielded markedly higher phenolic compound loadings, peaking at 43.79 mg ETA/g membrane at 11 MPa and 45 degrees C over 6 h, compared to 25.44 mg ETA/g membrane with conventional impregnation at ambient pressure and 45 degrees C over the same duration. (AU)

• FAPESP's process: 20/07575-2 - Application of high pressure technology to obtain bioproducts: assembly of a multi-purpose equipment and development of processes for barbatimão
• Grantee: Priscilla Carvalho Veggi
• Support Opportunities: Regular Research Grants