Novel 8%-TiO₂-nanoparticle-reinforced dense polycrystalline bovine hydroxyapatite bioceramic

Author(s)

de Azevedo-Silva, Lucas Jose ; Ferrairo, Brunna Mota ; Pires, Luara Aline ; Souza Padovini, David Santos ; Goncalves Dias, Leonardo Francisco ; Erbereli, Rogerio ; Fortulan, Carlos Alberto ; Lisboa-Filho, Paulo Noronha ; Rubo, Jose Henrique ; Sanches Borges, Ana Flavia

• Document type: Journal article
• Source: INTERNATIONAL JOURNAL OF CERAMIC ENGINEERING AND SCIENCE; v. 4, n. 3, p. 12-pg., 2022-05-01.

Abstract

This study aimed to produce and characterize the microstructure and mechanical properties of dense polycrystalline bovine hydroxyapatite (DPBHA) bioceramics with 5% and 8% of TiO2 nanoparticles after final synthetization for future use in dental implants. Structural characterization was obtained from analyzes by Fourier transform infrared spectroscopy, X-ray diffraction, scanning electron microscope, energy dispersive spectroscopy, and relative density and apparent porosity. The mechanical characterization was performed by measuring the fracture toughness after three-point flexural strength (FS) test. The microstructural characterization results showed no secondary phase formation and nonhomogeneous nanoparticle dispersion in HA matrix. DPBHA/Np8% (2.9 +/- 0.09 g/cm(3)) exhibited significantly greater density than DPBHA (2.7 +/- 0.03 g/cm(3)) (p = 0.011) and DPBHA/Np5% (2.7 +/- 0.05 g/cm(3)) (p = 0.041). DPBHA (0.9%) had the smallest porosity followed by DPBHA/Np8% (3.4%). DPBHA/Np5% (4.5%) exhibited the greatest proportion of pores. Pure HA (51.7 +/- 10.3 MPa) and DPBHA/Np8% (47.4 +/- 6.4 MPa) had significant greater FS (p < 0.001) than DPBHA/Np5% (28.8 +/- 3.1 MPa). DPBHA (0.43 +/- 0.01 MPa m(1/2)) and DPBHA/Np8% (0.40 +/- 0.06 MPa m(1/2)) presented greater KIc than DPBHA/Np5% (0.23 +/- 0.02 MPa m(1/2)) (p < 0.003; p < 0.007). In conclusion, 8% TiO2 nanoparticle addition to this synthesis would be a promising HA blend, as mechanical properties were similar, and the relative density/apparent porosity showed superior results than those of the DPBHA. (AU)

• FAPESP's process: 13/07296-2 - CDMF - Center for the Development of Functional Materials
• Grantee: Elson Longo da Silva
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 18/23639-0 - Manufacturing of dense bovine hydroxyapatite ceramics with added TiO2 nanoparticles: innovation for sustainability
• Grantee: Ana Flávia Sanches Borges
• Support Opportunities: Regular Research Grants
• FAPESP's process: 20/01715-7 - Synthesis and structural and mechanical characterization of dense bovine hydroxyapatite bioceramic with added Y-TZP nanoparticle and whiskers
• Grantee: Lucas José de Azevedo Silva
• Support Opportunities: Scholarships in Brazil - Doctorate