Nanobased Natural Polymers as a Carrier System for Glyphosate: An Interesting Approach Aimed at Sustainable Agriculture

Author(s)

Munhoz-Garcia, Gustavo Vinicios ; Takeshita, Vanessa ; de Oliveira, Jhones Luiz ; Dalla Vecchia, Bruno ; Nalin, Daniel ; Pinacio, Camila de Werk ; de Oliveira, Ana Laura Camachos ; Cardoso, Brian Cintra ; Tornisielo, Valdemar Luiz ; Fraceto, Leonardo Fernandes

• Document type: Journal article
• Source: Journal of Agricultural and Food Chemistry; v. 73, n. 2, p. 15-pg., 2025-01-02.

Abstract

Polymer-based herbicide nanocarriers have shown potential for increasing the herbicide efficacy and environmental safety. This study aimed to develop, characterize, and evaluate toxicity to target and nontarget organisms of natural-based polymeric nanosystems for glyphosate. Polymers such as chitosan (CS), zein (ZN), and lignin (LG) were used in the synthesis. Nanosystem size, surface charge, polydispersity index, encapsulation efficiency, toxicity to weed species (Amaranthus hybridus, Ipomoea grandifolia, and Eleusine indica), and Roundup Ready (RR) crops, soil respiration, and enzyme activity were evaluated. The most stable system was the combination of ZN with the cross-linker poloxamer (PL), with higher weed control efficacy (90-96%) for A. hybridus, compared to commercial glyphosate (40%). No improvement was observed for I. grandifolia and E. indica. No glyphosate toxicity was observed in RR crops, soil respiration, or soil enzymes, indicating no toxic effects of the nanoformulation in these models. ZN-PL systems can be a promising alternative for glyphosate delivery, using environmentally friendly materials, with improved efficiency for weed control in agriculture. (AU)

• FAPESP's process: 23/16519-7 - Double bioherbicide nanosystem as a sustainable strategy for weed control
• Grantee: Vanessa Takeshita
• Support Opportunities: Scholarships in Brazil - Post-Doctoral
• FAPESP's process: 22/16554-4 - Application of radiometric techniques to characterize the retention, mobility, toxicity, and degradation of herbicide nanocarrier systems in the environment
• Grantee: Valdemar Luiz Tornisielo
• Support Opportunities: Regular Research Grants
• FAPESP's process: 22/01554-9 - Impacts of metribuzin nanoformulation application on soil non-target organisms
• Grantee: Brian Cintra Cardoso
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 22/00718-8 - Glyphosate carrier nanosystems: from development to application in weed management
• Grantee: Gustavo Vinícios Munhoz Garcia
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 19/27255-5 - Multi-User Equipment approved in grant 2018/24432-0: Tecan infinite 200 pro multimode plate reader
• Grantee: Paulo José Pereira Lima Teixeira
• Support Opportunities: Multi-user Equipment Program
• FAPESP's process: 21/03455-5 - Straw-herbicide interaction in no-tillage system: effects of pre-emergent herbicides on the control of slender amaranth
• Grantee: Camila de Werk Pinácio
• Support Opportunities: Scholarships in Brazil - Scientific Initiation
• FAPESP's process: 21/10639-5 - Center for Research on Biodiversity Dynamics and Climate Change
• Grantee: Leonor Patricia Cerdeira Morellato
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC
• FAPESP's process: 19/04758-1 - Nanoparticles as a carrier of herbicides applied in pre-emergency system in soils derived from no-tillage and conventional
• Grantee: Vanessa Takeshita
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 22/12619-4 - Organic residues as materials reducing the impact of preemergent herbicides on soil microbial activity
• Grantee: Ana Laura Camachos de Oliveira
• Support Opportunities: Scholarships in Brazil - Scientific Initiation