Extraction techniques for propolis and its utilization in silver nanoparticle synthesis: a comprehensive review

Author(s)

Mancano, Rosana Rabelo ; Matheus, Larissa Resende ; Castro, Luiz Eduardo Nochi ; Barroso, Tiago Linhares Cruz Tabosa ; da Rosa, Rafael Gabriel ; Ferreira, Vanessa Cosme ; Forster-Carneiro, Tania ; Colpini, Leda Maria Saragiotto

• Document type: Journal article
• Source: EUROPEAN FOOD RESEARCH AND TECHNOLOGY; v. N/A, p. 37-pg., 2025-04-05.

Abstract

Propolis, a resinous substance collected by bees from plant sources, is rich in flavonoids and phenolic acids, endowing it with significant antibacterial and anti-inflammatory properties. This comprehensive review and bibliometric analysis examines research progress, updates, trends, and perspectives on the use of propolis and its application in silver nanoparticles (AgNPs). A total of 493 papers investigated propolis extraction and its application in nanoparticles over the last 14 years. The bibliometric analysis revealed a growing interest in this natural substance, as evidenced by the increase in publication trends and the emergence of relevant keywords. The increasing co-occurrence of terms such as "green synthesis", "antibacterial activity", and "bioactive compounds" reflects the growing interest in the sustainable development of nanoparticles. This expanding body of research is crucial in addressing global health concerns and providing sustainable therapeutic options and innovative applications. The analysis identified significant contributions to these fields, suggesting a promising future for exploiting these substances to enhance efficacy and safety in healthcare, food safety, and environmental applications. The evolving research landscape reveals a trajectory toward the integration of natural substances with advanced technologies, potentially leading to significant advances such as combating antibiotic-resistant pathogens in the medical field and their use as environmentally friendly agricultural pesticides and plant growth enhancers. This review underscores the importance of these natural compounds and their potential for further development. As interest continues to grow, the promise of propolis and AgNPs to provide effective, safe, and sustainable solutions remains a focal point for future research and applications. (AU)

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• Grantee: Vanessa Cosme Ferreira
• Support Opportunities: Scholarships in Brazil - Doctorate
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• Grantee: Luiz Eduardo Nochi de Castro
• Support Opportunities: Scholarships in Brazil - Doctorate
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• Support Opportunities: Scholarships in Brazil - Doctorate