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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Phytochemical screening, antioxidant, and antimicrobial activities of the crude leaves extract from Ipomoea batatas (L.) Lam

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Author(s):
Pochapski, Marcia Thais [1] ; Fosquiera, Eliana Cristina [2] ; Esmerino, Luis Antonio [3] ; dos Santos, Elizabete Brasil [2] ; Farago, Paulo Vitor [3] ; Santos, Fabio Andre [2] ; Groppo, Francisco Carlos [1]
Total Authors: 7
Affiliation:
[1] Univ Estadual Campinas, Piracicaba Dent Sch, Dept Pharmacol Anesthesiol & Therapeut, Piracicaba, SP - Brazil
[2] Univ Estadual Ponta Grossa, Dept Dent, Ponta Grossa, Parana - Brazil
[3] Univ Estadual Ponta Grossa, Dept Pharm, Ponta Grossa, Parana - Brazil
Total Affiliations: 3
Document type: Journal article
Source: PHARMACOGNOSY MAGAZINE; v. 7, n. 26, p. 165-170, APR-JUN 2011.
Web of Science Citations: 27
Abstract

Background: Ipomoea batatas (L.) Lam., popularly known as sweet potato (SP), has played an important role as an energy and a phytochemical source in human nutrition and animal feeding. Ethnopharmacological data show that SP leaves have been effectively used in herbal medicine to treat inflammatory and/or infectious oral diseases in Brazil. The aim of this research was to evaluate the phytochemical, antioxidant, and antimicrobial activities of the crude leaves extract of SP leaves. Materials and Methods: The screening was performed for triterpenes/steroids, alkaloids, anthraquinones, coumarins, flavonoids, saponins, tannins, and phenolic acids. The color intensity or the precipitate formation was used as analytical responses to these tests. The total antioxidant capacity was evaluated by the phosphomolybdenum complex method. Antimicrobial activity was made by agar disk and agar well diffusion tests. Results: The phytochemical screening showed positive results for triterpenes/steroids, alkaloids, anthraquinones, coumarins, flavonoids, saponins, tannins, and phenolic acids. Total contents of 345.65, 328.44, and 662.02 mg were respectively obtained for alkaloids, anthraquinones, and phenolic compounds in 100 g of the dry sample. The total antioxidant capacity was 42.94 as compared to ascorbic acid. For antimicrobial studies, no concentration of the SP freeze dried extract was able to inhibit the growth of Streptococcus mutans, S. mitis, Staphylococcus aureus, and Candida albicans in both agar disk and agar well diffusion tests. Conclusions: SP leaves demonstrated the presence of secondary metabolites with potential biological activities. No antimicrobial activity was observed. (AU)

FAPESP's process: 08/00734-6 - The effects of Ipomoea batatas L on inflammation and against dental biofilm.
Grantee:Márcia Thaís Pochapski
Support Opportunities: Scholarships in Brazil - Doctorate