Chiral organoselenium-transition-metal catalysts in asymmetric transformations

Author(s)

Godoi, Marcelo ^[1] ; Paixao, Marcio W. ^[2] ; Braga, Antonio L. ^[1]

Affiliation

^[1] Univ Fed Santa Catarina, Dept Quim, BR-88040970 Florianopolis, SC - Brazil

^[2] Univ Fed Sao Carlos, Dept Quim, Lab Sintese Prod Nat, BR-13560 Sao Carlos, SP - Brazil

• Document type: Journal article
• Source: DALTON TRANSACTIONS; v. 40, n. 43, p. 11347-11355, 2011.
• Web of Science Citations: 71

Abstract

In recent years, there has been an increasing application of chiral selenium compounds as ligands in metal-catalyzed enantioselective transformations. One of the most important challenges in this field is the development of new chiral complexes (catalyst) generated from the reaction between a metal and appropriate chiral selenium-containing compounds (ligand). The vast majority of these ligands are easily synthesized in a few high-yielding synthetic steps, starting from readily available chiral amino alcohols. In this context, the advantages of using these compounds will be discussed, mainly with regard to their easy accessibility, modular nature and the formation of strong bonds with soft or, more rarely, hard metals. Important selective contributions within the field of chiral selenium complexes are examined, according to their applications. As final remarks, future developments and perspectives of the field are discussed. (AU)

• FAPESP's process: 09/07281-0 - Asymmetric organocatalysis: design of new organocatalysts and development of new methodologies
• Grantee: Márcio Weber Paixão
• Support Opportunities: Research Grants - Young Investigators Grants