Aspergillus sp lipase: Potential biocatalyst for industrial use

Author(s)

Contesini, Fabiano Jares ^[1] ; Lopes, Danielle Branta ^[1] ; Macedo, Gabriela Alves ^[1] ; Nascimento, Maria da Graca ^[2] ; Carvalho, Patricia de Oliveira ^[3]

Affiliation

^[1] Univ Estadual Campinas UNICAMP, Lab Bioquim Alimentos, Fac Engn Alimentos, BR-13083862 Sao Paulo - Brazil

^[2] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC - Brazil

^[3] Univ Sao Francisco, BR-12916900 Sao Paulo - Brazil

• Document type: Review article
• Source: JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC; v. 67, n. 3-4, p. 163-171, DEC 2010.
• Web of Science Citations: 91

Abstract

The lipases obtained from the genus Aspergillus present remarkable importance in biotechnological applications, and numerous studies have reported the importance of the fermentation parameters, such as nutrients, temperature and fermentation time. Moreover, many Aspergillus spp. lipases present several properties of immense industrial importance, such as their pH and temperature stability and excellent enantioselectivity. Different strategies have been used in order to immobilize crude or purified Aspergillus spp. lipases. Hence, Aspergillus spp. lipases have been studied for different industrial applications such as in the food and detergent industries, and also in the kinetic resolution of pharmaceuticals and chiral intermediates. This review highlights the production, purification, characterization, applications and immobilization of lipases from Aspergillus spp. (C) 2010 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 06/01393-2 - Purification and immobilization of the native microbial lipases for the enantioselective esterification of racemic ibuprofen
• Grantee: Patrícia de Oliveira Carvalho
• Support Opportunities: Regular Research Grants
• FAPESP's process: 08/01235-3 - Biocatalysis in health: obtaining biological active lipids by immobilized lipases
• Grantee: Patrícia de Oliveira Carvalho
• Support Opportunities: Regular Research Grants