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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Paradoxical sleep deprivation: neurochemical, hormonal and behavioral alterations. Evidence from 30 years of research

Full text
Author(s):
Tufik, Sergio [1] ; Andersen, Monica L. [1] ; Bittencourt, Lia R. A. [1] ; de Mello, Marco T. [1]
Total Authors: 4
Affiliation:
[1] Univ Fed Sao Paulo, Escola Paulista Med, Dept Psicobiol, Disciplina Med & Biol Sono, BR-04024002 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Anais da Academia Brasileira de Ciências; v. 81, n. 3, p. 521-538, SEP 2009.
Web of Science Citations: 74
Abstract

Sleep comprises approximately one-third of a person's lifetime, but its impact on health and medical conditions remains partially unrecognized. The prevalence of sleep disorders is increasing in modern societies, with significant repercussions on people's well-being. This article reviews past and current literature on the paradoxical sleep deprivation method as well as data on its consequences to animals, ranging from behavioral changes to alterations in the gene expression. More specifically, we highlight relevant experimental studies and our group's contribution over the last three decades. (AU)

FAPESP's process: 98/14303-3 - Center for Sleep Studies
Grantee:Sergio Tufik
Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC